summer@coreychem.com
| Price | USD3.00 |
| Packge | 1KG |
- Min. Order:1KG
- Supply Ability:1kg,5kg,50kg
- Time:2020-01-19
Product Details
- Product NameHosenkoside A
- CAS No.156791-82-1
- MFC48H82O20
- MW979.15
- AppearanceSolidWhite to off-white
- Boiling point 1075.9±65.0 °C(Predicted)
- density 1.44±0.1 g/cm3(Predicted)
Names
Name 8,19-Secolupane, β-D-glucopyranoside deriv.
Synonym More Synonyms
Hosenkoside A Biological Activity
Description Hosenkoside A is a baccharane glycoside isolated from the seeds of impatiens balsamina.
Related Catalog
Signaling Pathways >> Others >> Others
Natural Products >> Saccharides and Glycosides
Research Areas >> Inflammation/Immunology
In Vivo The mean peak concentrations of hosenkoside A in rats after oral administration of total saponins of Semen Impatientis is 162.08±139.87 ng/mL, occurring at times of 0.67 h. The terminal half-lives of hosenkoside A is 5.39±2.06h[1].
Animal Admin Male Wistar rats (7 weeks old, 220±20 g, n=6) are fasted for 12 h. Total saponins of Semen Impatientis at a dose of 300 mg (in 10 mL)/kg are orally administered to rats using a gastric gavage tube. The doses of hosenkoside A is12.4 mg/kg for an oral dose of 300 mg/kg total saponins. Blood samples (0.20 mL) are collected from suborbital vein into heparinized tubes before administration (0 min), and 0.08, 0.25, 0.5, 0.75, 1, 1.5, 2, 4, 6, 8, 12 and 24 h after dosing.
References
[1]. Yu X, et al. An LC-MS/MS method for simultaneous determination of hosenkoside A and hosenkoside K from Semen Impatientis in rat plasma and its application to a pharmacokinetic study. Biomed Chromatogr. 2017 Mar;31(3).
Chemical & Physical Properties
Density 1.4±0.1 g/cm3
Boiling Point 1075.9±65.0 °C at 760 mmHg
Molecular Formula C48H82O20
Molecular Weight 979.153
Flash Point 604.5±34.3 °C
Exact Mass 978.539917
PSA 327.60000
LogP 0.07
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.626
Synonyms
β-D-Glucopyranoside, (1R,2S,4aR,4bR,6'S,6aR,7R,8S,10aR,10bR,12aS)-7-[(β-D-glucopyranosyloxy)methyl]octadecahydro-1-hydroxy-6'-[(1S)-2-hydroxy-1-methylethyl]-4a,4b,7,10a-tetramethylspiro[chrysene -2(1H),3'(4'H)-[2H]pyran]-8-yl 2-O-β-D-glucopyranosyl-
(1R,2S,4aR,4bR,6'S,6aR,7R,8S,10aR,10bR,12aS)-7-[(β-D-Glucopyranosyloxy)methyl]-1-hydroxy-6'-[(2S)-1-hydroxy-2-propanyl]-4a,4b,7,10a-tetramethyloctadecahydro-1H,4'H-spiro[chrysene-2,3'-pyran]-8-yl 2 -O-β-D-glucopyranosyl-β-D-glucopyranoside
Hosenkoside A
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
- Since:2014-12-17
- Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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