iOWH-032
| Price | USD1.00 |
| Packge | 1g |
- Min. Order:1g
- Supply Ability:200kg
- Time:2020-01-14
Product Details
- Product Name iOWH-032
- CAS No.1191252-49-9
- MFC22H15Br2N3O4
- MW545.18
- AppearancesolidWhite to off-white
- density 1.670±0.06 g/cm3(Predicted)
- storage temp. 2-8°C
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Product Name:
Synonyms:
1,2,4-Oxadiazole-5-carboxamide, 3-(3,5-dibromo-4-hydroxyphenyl)-N-[(4-phenoxyphenyl)methyl]-;3-(3,5-Dibromo-4-hydroxyphenyl)-N-[(4-phenoxyphenyl)methyl]-1,2,4-oxadiazole-5-carboxamide IOWH032;iOWH-032;3-(3,5-Dibromo-4-hydroxyphenyl)-N-[(4-phenoxyphenyl)methyl]-1,2,4-oxadiazole-5-carboxamide;3-(3,5-DibroMo-4-hydroxyphenyl)-N-(4-phenoxybenzyl)-1,2,4-oxadiazole-5-carboxaMide
CAS:
MF:
C22H15Br2N3O4
MW:
545.1802
EINECS:
Product Categories:
Mol File:
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iOWH-032 Chemical Properties
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density
1.670±0.06 g/cm3(Predicted)
pka
3.34±0.46(Predicted)
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Safety Information
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iOWH-032 Usage And Synthesis
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IOWH032 is a synthetic CFTR inhibitor with IC50 of 1.01 μM in CHO-CFTR cell based assays. Phase 2.
IOWH032 shows inhibitory activity against CFTR in T84-CFTR cell based assays with IC50 of 6.87 μM.
In a mouse closed-loop model, IOWH032 causes a statistical significant inhibition against cholera toxin (CTX) induced secretion. IOWH032 (5 mg/kg) reduces the fecal output index by ~70% in a cecetomized rat model.
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iOWH-032 Preparation Products And Raw materials
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
- Since:2014-12-17
- Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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