CILAZAPRIL
| Price | USD1.00 |
| Packge | 1g |
- Min. Order:1g
- Supply Ability:200kg
- Time:2020-01-13
Product Details
- Product Name CILAZAPRIL
- CAS No.92077-78-6
- EINECS No.200-258-5
- MFC22H31N3O5.H2O
- MW435.51
- AppearanceneatWhite to off-white
- Melting point 98° (dec)
- storage temp. Store at -20°C
Mary
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Product Name:
Synonyms:
Initiss;Justor;Vascase;9-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]-10-oxo-1,2,3,4,6,7,8,9-oc tahydropyridazino[1,2-a]diazepine-1-carboxylic acid;9[[1-ETHOXYCARBONYL-3-PHENYLPROPYL]AMINO]OCTAHYDRO-10-OXO-6HPYRIDAZINO[1,2-A][1,2]DIAZEPINE-1-CARBOXYLIC ACID;CILAZAPRIL EPC(;CILAZAPRIL EPC(CRM STANDARD);CILAZAPRIL IMPURITY A1,1-DIMETHYLETHYL(1S,9S)-9-[[(S)-1-ETHOXYCARBONYL-3-PHENYLPROPYL]AMINO]-10-OXO-OCTAHYDRO-6H-PYRIDAZINO[1,2A][1,2]DIAZEPINE-1-CABOXYLATE EPC
CAS:
MF:
C22H33N3O6
MW:
435.51
EINECS:
Product Categories:
Mol File:
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CILAZAPRIL Chemical Properties
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Melting point
98° (dec)
alpha
D20 -62.51° (c = 1% in ethanol)
solubility
Slightly soluble in water, freely soluble in methanol and in methylene chloride.
form
neat
pka
pKa1 3.3; pKa2 6.4(at 25℃)
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Safety Information
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CILAZAPRIL Usage And Synthesis
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Description
Cilazapril is a new ACE inhibitor useful in the management of mild to moderate hypertension. Orally administered cilazapril is a prodrug which is de-esterified to its active diacid metabolite cilazprilat. Compared with enalapril and captopril, cilazapril is more potent and longer lasting.
Chemical Properties
White or almost white, crystalline powder.
Originator
Hoffmann-LaRoche (Switzerland)
Uses
Antihypertensive.
Brand name
Inhibace (Hoffmann-LaRoche).
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CILAZAPRIL Preparation Products And Raw materials
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Raw materials
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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- Since:2014-12-17
- Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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