GO 6976
| Price | USD1.00 |
| Packge | 1g |
- Min. Order:1g
- Supply Ability:200kg
- Time:2020-01-13
Product Details
- Product NameGO 6976
- CAS No.136194-77-9
- EINECS No.200-258-5
- MFC24H18N4O
- MW378.43
- AppearanceOff-white solidWhite to Off-White
- storage temp. Sealed in dry,2-8°C
- Boiling point 652.3±55.0 °C(Predicted)
- density 1.41±0.1 g/cm3(Predicted)
- Melting point >221°C (dec.)
Mary
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Product Name:
Synonyms:
InSolution G 6976 - CAS 136194-77-9 - Calbiochem;5,6,7,13-Tetrahydro-13-methyl-5-oxo-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile;Go6976,5,6,7,13-Tetrahydro-13-Methyl-5-oxo-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile;PD406976;InSolution? G? 6976;12-(2-CYANOETHYL)-6,7,12,13-TETRAHYDRO-13-METHYL-5-OXO-5H-INDOLO(2,3-A)PYRROLO(3,4-C)-CARBAZOLE;12-2(2-CYANOETHYL)-6,7,12,13-TETRAHYDRO-13-METHYL-5-OXO-5H-INDOLO[2,3-A]PYRROLO[3,4-C]CARBAZOLE;GO 6976
CAS:
MF:
C24H18N4O
MW:
378.43
EINECS:
Product Categories:
Mol File:
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GO 6976 Chemical Properties
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Boiling point
652.3±55.0 °C(Predicted)
density
1.41±0.1 g/cm3(Predicted)
storage temp.
−20°C
form
Off-white solid
pka
14.39±0.20(Predicted)
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Safety Information
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Safety Statements
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GO 6976 Usage And Synthesis
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Biological Activity
Potent protein kinase C (PKC) inhibitor (IC 50 = 7.9 nM). In vitro, discriminates between Ca 2+ -dependent and -independent isoforms of PKC; selectively inhibits PKC α and PKC β 1 (IC 50 values are 2.3 and 6.2 nM respectively) but does not inhibit the activity of PKC δ , - ε , or - ζ (IC 50 > 3 μ M). Also inhibits TrkA, TrkB, JAK2 and JAK3 tyrosine kinases (IC 50 values are 5, 30, 130 and 370 nM respectively).
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GO 6976 Preparation Products And Raw materials
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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- Since:2014-12-17
- Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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