Paricalcitol
| Price | USD0.01 |
| Packge | 1KG |
- Min. Order:1KG
- Supply Ability:1kg; 5kg; 10kg；25kg
- Time:2020-01-08
Product Details
- Product NameParicalcitol
- CAS No.131918-61-1
- EINECS No.658-064-6
- MFC27H44O3
- MW416.65
- AppearanceneatWhite to off-white
- Boiling point 564.8±50.0 °C(Predicted)
- density 1.121±0.06 g/cm3(Predicted)
- storage temp. Store at -20°C,unstable in solution, ready to use.
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Product Name:
Synonyms:
PARICALCITOL (10 MG)F0E3030.997MG/MG(AI);PARICALCITOL;19-nor-1alpha,25-dihydroxyvitamin D2;(1R,3R)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5S)-6-Hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]cyclohexane-1,3-diol;Zemplar;1,3-Cyclohexanediol, 5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E,4S)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3R,5Z)-;Paricalcitol (10 mg) (COLD SHIPMENT REQUIRED);(1R,3R,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-Octahydro-1-[(1R,2E,4S)-5-hydroxy-1,4,5-triMethyl-2-hexen-1-yl]-7a-Methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol
CAS:
MF:
C27H44O3
MW:
416.64
EINECS:
658-064-6
Product Categories:
Mol File:
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Paricalcitol Chemical Properties
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Boiling point
564.8±50.0 °C(Predicted)
density
1.121±0.06 g/cm3(Predicted)
Fp
14℃
pka
14.34±0.40(Predicted)
form
neat
InChIKey
BPKAHTKRCLCHEA-UBFJEZKGSA-N
CAS DataBase Reference
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Safety Information
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RIDADR
UN1170 - class 3 - PG 2 - Ethanol, solution
HS Code
2936299055
Hazardous Substances Data
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Paricalcitol Usage And Synthesis
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Description
Paricalcitol was launched as Zemplar in the US for the prevention and treatment of secondary hyperthyroidism associated with chronic renal failure. Paricalcitol is a synthetic vitamin D2, namely a novel 1-alpha-hydroxy-19-noranalogue in which the ring A exocyclic methylene group, typical of all vitamin D systems, has been replaced by two hydrogen atoms. Paricalcitol is the first vitamin D analogue marketed for this indication. In patients with chronic renal failure, Paricalcitol appreciably reduced levels of parathyroid hormone (PTH) without a significant difference in the incidence rate for hypercalcemia or hyperphosphatemia when compared with placebo.
Chemical Properties
White Solid
Originator
Abbott (US)
Uses
Synthetic analog of vitamin D. Antihyperparathyroid.
Uses
Antihyperparathyriod
Uses
1,25-Dihydroxy vitamin D2 is a potent agonist of the vitamin D receptor. Paricalcitol is a synthetic 1,25-dihydroxy vitamin D2 analog. As vitamin D deficiency, associated with chronic kidney disease, leads to an increase in parathyroid hormone (secondary hyperparathyroidism), paricalcitol is used in renal patients to block parathyroid hormone overproduction. Vitamin D deficiency is also a risk factor in cancer, cardiovascular disease, hypertension, and diabetes, and paricalcitol may have applications in those contexts as well.
Brand name
Zemplar (Abbott).
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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- Since:2014-12-17
- Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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