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OLSALAZINE
OLSALAZINE

OLSALAZINE

Price USD1.00
Packge 1KG
  • Min. Order:1KG
  • Supply Ability:1ton
  • Time:2020-01-05

Product Details

  • Product NameOLSALAZINE
  • CAS No.15722-48-2
  • EINECS No.200-258-5
  • MFC14H10N2O6
  • MW302.24
  • AppearanceSolidLight yellow to yellow
  • Boiling point 443.29°C (rough estimate)
  • density 1.3578 (rough estimate)
  • Melting point >300 °C(Solv: acetic acid (64-19-7); water (7732-18-5))
  • Water Solubility 11.49ug/L(25 ºC)
OLSALAZINE Basic information
Product Name:
Synonyms:
Olsalazine-13C6;Ph-CJ-91B;OLSALAZINE;4,4'-Dihydroxyazobenzene-3,3'-dicarboxylic acid;5,5'-Azodisalicylic acid;3,3'-(1,2-diazenediyl)bis[6-hydroxy-Benzoic acid;3,3’-azobis(6-hydroxy-benzoicaci;3,3’-azobis(6-hydroxybenzoicacid)
CAS:
MF:
C14H10N2O6
MW:
302.24
EINECS:
605-089-5
Product Categories:
 
Mol File:
OLSALAZINE Structure
 
OLSALAZINE Chemical Properties
Melting point 
>300 °C(Solv: acetic acid (64-19-7); water (7732-18-5))
Boiling point 
443.29°C (rough estimate)
density 
1.3578 (rough estimate)
refractive index 
1.6500 (estimate)
pka
2.40±0.10(Predicted)
CAS DataBase Reference
 
Safety Information
MSDS Information
 
 
OLSALAZINE Usage And Synthesis
Uses
Anti-inflammatory (gastrointestinal).
Indications
Olsalazine is approved for maintenance of remission of ulcerative colitis, but a commonly reported side effect is a paradoxical increase in diarrhea. The U. S. Food and Drug Administration (FDA) has approved balsalazide disodium (Colazal) as a treatment of mild to moderately active ulcerative colitis.
Definition
ChEBI: An azobenzene that consists of two molecules of 4-aminosalicylic acid joined by an azo linkage. A prodrug for mesalazine, an anti-inflammatory drug, it is used (as the disodium salt) in the treatment of inflammatory bowel disease.
Brand name
Dipentum (UCB).
Mechanism of action
Olsalazine is approved for maintenance of remission of ulcerative colitis, but a commonly reported side effect is a paradoxical increase in diarrhea. The U. S. Food and Drug Administration (FDA) has approved balsalazide disodium (Colazal) as a treatment of mild to moderately active ulcerative colitis.
Veterinary Drugs and Treatments
Olsalazine is used for treatment of dogs with chronic colitis that either cannot tolerate the adverse effects associated with sulfasalazine or the response to sulfasalazine has been ineffective.

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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  • Since:2014-12-17
  • Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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