CGP 57380
Price | USD1.00 |
Packge | 1g |
- Min. Order:1g
- Supply Ability:200kg
- Time:2019-12-26
Product Details
- Product NameCGP 57380
- CAS No.522629-08-9
- MFC11H9FN6
- MW244.23
- Appearancepowderwhite to beige
- storage temp. 2-8°C
Mary
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Product Name:
Synonyms:
MNK1 Inhibitor - CAS 522629-08-9 - Calbiochem;CGP 57380;CGP57380, N3-(4-fluorophenyl)-1h-pyrazolo[3,4-d]pyrimidine-3,4-diamine;MNK1 Inhibitor;N3-(4-Fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine
CAS:
MF:
C11H9FN6
MW:
244.232
EINECS:
Product Categories:
Mol File:
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CGP 57380 Chemical Properties
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storage temp.
2-8°C
solubility
DMSO: soluble10mg/mL, clear
form
powder
color
white to beige
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Safety Information
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WGK Germany
3
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CGP 57380 Usage And Synthesis
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Biological Activity
Inhibitor of MAP-kinase interacting kinase-1 (Mnk1, MKNK1) (IC 50 = 2.2 μ M) that displays selectivity over p38, JNK1, ERK1, ERK2, PKC and c-src family kinases. Blocks phosphorylation of eIF4E in cellular assays (IC 50 = 3 μ M) and inhibits LPS-induced TNF α expression in macrophages.
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CGP 57380 Preparation Products And Raw materials
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates:
Pharmaceutical intermediates;
OLED intermediates;
- Since:2014-12-17
- Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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