3--Phenyl-N-(2,2,2-trichloro-1-((((4-chlorophenyl)amino)carbonothioyl)amino)ethyl)acrylamide
| Price | USD1.00 |
| Packge | 1KG |
- Min. Order:1KG
- Supply Ability:100kgs
- Time:2019-12-20
Product Details
- Product NameIWR-1-endo
- CAS No.1127442-82-3
- MFC25H19N3O3
- MW409.44
- AppearanceLiquidwhite to beige
- storage temp. room temp
- Boiling point 643.9±55.0 °C(Predicted)
- density 1.425±0.06 g/cm3(Predicted)
Mary 0003
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Product Name:
Synonyms:
rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide IWR-1-endo;IWR-1-endo, >=98%;IWR-1(IWR-1-endo);4-(1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl)-N-8-quinolinyl-Benzamide (IWR-1);[(3aR*,4S*,7R*,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide;endo-IWR 1;IWR-1-endo - IWR-1 | endo-IWR-1;IWR-1
CAS:
MF:
C25H19N3O3
MW:
409
EINECS:
Product Categories:
Mol File:
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IWR-1-endo Chemical Properties
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alpha
-3.0～+3.0°(20℃/D)(c=0.1,CH3CN)
Boiling point
643.9±55.0 °C(Predicted)
density
1.425±0.06 g/cm3(Predicted)
storage temp.
Store at RT
solubility
DMSO: soluble5mg/mL, clear
form
Liquid
pka
11.88±0.43(Predicted)
color
white to beige
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Safety Information
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WGK Germany
3
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IWR-1-endo Usage And Synthesis
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Uses
IWR-1-endo act as inhibitors of Wnt response. It appear that IWR compounds induce stabilization of Axin proteins via a direct interaction, which is a part of the b-catenin destruction complex (consists of Apc, Axin, Ck1 and Gsk3b). Such compounds may be used in the treatment of Wnt protein signaling-related diseases and conditions such as cancer, degenerative diseases, type II diabetes and osteopetrosi s.
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IWR-1-endo Preparation Products And Raw materials
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Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
- Since:2014-12-17
- Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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