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HomecompanyFactory high quality and low price Cefatrizine
Cefatrizine
Cefatrizine
Cefatrizine
Cefatrizine
Cefatrizine

Factory high quality and low price Cefatrizine

Price USD1.00
Packge 1KG
  • Min. Order:1KG
  • Supply Ability:KG/T
  • Time:2019-12-20

Product Details

  • Product NameCefatrizine
  • CAS No.51627-14-6
  • EINECS No.257-324-2
  • MFC18H18N6O5S2
  • MW462.5
  • density 1.3806 (rough estimate)
  • Boiling point 948.1±65.0 °C(Predicted)
  • Water Solubility Water: 95 mg/mL (201.02 mM)
  • storage temp. Store at -20°C
heidi51
Product Name:
Synonyms:
cephatriazine;eta(r)))-;l)acetyl)amino)-8-oxo-3-((1h-1,2,3-triazol-4-ylthio)methyl)-,(6r-(6-alpha,7-b;s640p;Cephathiamidine;CEFATRIZINE IMPURITY A7-AMINO-(6R,7R)-3-[(2H-1,2,3-TRIAZOL-4-YL)SULFANYL]-METHYL-8-OXO-5-THIA-1-AZABICYCLO[4.2.O]OCT-2-ENE-2-CARBOXYLIC ACID(7-ACA TRIAZOLE) EPC(CRM STANDARD);CEFATRIZINE;CEFATRIZINE PROPYLENE GLYCOL
CAS:
MF:
C18H18N6O5S2
MW:
462.51
EINECS:
257-324-2
Product Categories:
Mol File:
Cefatrizine Structure
 
Cefatrizine Chemical Properties
Boiling point 
948.1±65.0 °C(Predicted)
density 
1.3806 (rough estimate)
refractive index 
1.7000 (estimate)
pka
2?+-.0.50(Predicted)
CAS DataBase Reference
 
Safety Information
Toxicity
LD50 in male, female mice, male, female rats (mg/kg): 6880, 6410, 4325, 4325 i.p. (Matsuzaki)
MSDS Information
 
 
Cefatrizine Usage And Synthesis
Uses
Antidepressant, Selective serotonin reuptake inhibitor
Definition
ChEBI: A cephalosporin compound having (1H-1,2,3-triazol-4-ylsulfanyl)methyl and [(2R)-2-amino-2-(4-hydroxyphenyl)]acetamido side-groups. An antibacterial drug first prepared in the 1970s, it has more recently been found to be n inhibitor of eukaryotic elongation factor-2 kinase (eEF2K), which is known to regulate apoptosis, autophagy and ER stress in many types of human cancers.
Antimicrobial activity
A semisynthetic cephalosporin formulated for oral use. The spectrum is similar to that of cefalexin but it is more active against H. influenzae. Wide strain variations in susceptibility have been reported.
It is only partially absorbed when given by mouth. A 500 mg oral dose achieves a concentration of c. 6 mg/L after 1–2 h. The normal half-life of 2.5 h is extended to 5.5 h in end-stage renal failure. Distribution resembles that of cefalexin. It crosses the placenta readily. Plasma protein binding is 40–60%.
Urinary recovery in 6 h is 35% of an oral dose, producing urinary levels of 50–1500 mg/L. It is presumed that the remainder is metabolized, but no metabolites have been identified.
Apart from some mild diarrhea, it is well tolerated. It is available in Japan.

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;
  • Since:2014-12-17
  • Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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