99% High Purity Methotrexate
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- Supply Ability:500MT
- Time:2021-07-09
Product Details
- Product Name99% High Purity Methotrexate
- CAS No.59-05-2
- EINECS No.200-413-8
- MFC20H22N8O5
- MW454.45
- InChIKeyFBOZXECLQNJBKD-VHLFKADZNA-N
- AppearancepowderLight yellow to yellow
- Water Solubility Insoluble. <0.1 g/100 mL at 19 ºC
- storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- Melting point 195°C
- Boiling point 561.26°C (rough estimate)
- density 1.4080 (rough estimate)
Application
Methotrexate is a drug used for the treatment of cancer, also known as cytotoxic drugs. In order to reduce its cytotoxicity, it can be used in conjunction with calcium leucovorin. It is primarily used for the treatment of acute leukemia (acute lymphocytic leukemia), breast cancer, malignant mole and choriocarcinoma, head and neck cancer, bone cancer, leukemia, spinal cord meningeal infiltration, lung cancer, reproductive system cancer, liver cancer, refractory psoriasis vulgaris, dermatomyositis, body myositis, ankylosing spondylitis inflammation, Crohn's disease, psoriasis and psoriatic arthritis, Behcet's disease and autoimmune disease.
Product Description
Product Name: Methotrexate
Synonyms: Methotrexate; Methylaminopterin; Methylaminopterine;antifolan;L-(+)-Amethopterin; 4-Amino-N 10-methylpteroyl-L-glutamic acid; 4-Amino-10-methylpteroyl-L-glutamic acid ;(+)-4-Amino-10-Methylfolic acid; N-(p-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)-L-glutamic acid
CAS NO: 59-05-2
Molecular formula: C20H22N8O5
Molecular weight: 454.44
Appearance: Yellow or Orange crystal powder
Assay: 98%-102%
Packing: 1kg/bag; 5kg/tin or 25kg/drum
Ridadr: UN2811,Class6.1,PGIII
Usage: Used as a antineoplastic and antirheumatic. A folic Acid antagonist
Specification
Characters
Yellow or orange crystalline, hygroscopic powder
Identification(IR)
The IR spectrum of sample exhibits maxima only at the same wavelength as that a similar preparation of methotrexate CRS.
Solubility:
Practically insoluble in water,I n ethanol[96 per cent] and in methylene chloride. It dissolves in dilute mineral acids and in dilute solutions of alkali hydroxides and carbonates.
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