AG 1478 HYDROCHLORIDE
| Price | USD1.00 |
| Packge | 1KG |
- Min. Order:1KG
- Supply Ability:20kg
- Time:2019-09-06
Product Details
- Product NameAG 1478 HYDROCHLORIDE
- CAS No.153436-53-4
- MFC16H14ClN3O2
- MW315.75
- AppearanceWhite to light yellow solid.Light orange to Yellow to Green
- storage temp. Keep in dark place,Inert atmosphere,2-8°C
- density 1.337
- Boiling point 458.5±45.0 °C(Predicted)
- Melting point 247 °C(dec.)
Abby040
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AG 1478 HYDROCHLORIDE Basic information
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Product Name:
Synonyms:
AG-1478 (NSC-693255);AG-1478, 97.5%, a selective EGFR inhibitor;N-(3-CHLOROPHENYL)-6,7-DIMETHOXY-4-QUINAZOLINANINE HYDROCHLORIDE;4-(3-CHLOROANILINO)-6,7-DIMETHOXYQUINAZOLINE HCL;4-(3-CHLOROANILINO)-6,7-DIMETHOXYQUINAZOLINE HYDROCHLORIDE;AG-1478;AG 1478 HYDROCHLORIDE;AG1478HCl
CAS:
MF:
C16H15Cl2N3O2
MW:
352.22
EINECS:
Product Categories:
Mol File:
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AG 1478 HYDROCHLORIDE Chemical Properties
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density
1.337
storage temp.
Desiccate at -20°C
form
White to light yellow solid.
λmax
332nm(lit.)
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Safety Information
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RTECS
VA0953000
HS Code
29339900
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AG 1478 HYDROCHLORIDE Usage And Synthesis
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Uses
A highly potent and specific EGFR tyrosine kinase inhibitor with an IC50 of 3 nM.
Biological Activity
Potent and selective inhibitor of epidermal growth factor receptor kinase (IC 50 values 3 nM for EGFR and > 100 μ M for ErbB2 and PDGFR). Inhibits proliferation of NCI-H2170 NSCLC cells in vitro (IC 50 = 1 μ M).
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Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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