3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide
Price | USD1.00 |
Packge | 1ASSAYS |
- Min. Order:1ASSAYS
- Supply Ability:10kg
- Time:2019-09-05
Product Details
- Product Name3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide
- CAS No.199666-03-0
- MFC17H15N3O6S2
- MW421.45
- AppearanceYellow solidfaint yellow to yellow
- storage temp. 2-8°C
- density 1.471±0.06 g/cm3 (20 ºC 760 Torr)
- Melting point 185℃
- Boiling point 627.4±65.0 °C(Predicted)
Abby009
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3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Basic information
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Synonyms:
KMO Inhibitor I, Ro 61-8048 - CAS 199666-03-0 - Calbiochem;3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide RO61-8048;RO 61-8048 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide;Ro 61-8048, >=98%;RO61-80483,4-dimethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)Benzenesulfonamide;KMO Inhibitor I, Ro 61-8048;3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide;3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide
CAS:
MF:
C17H15N3O6S2
MW:
0
EINECS:
Product Categories:
Mol File:
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3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Chemical Properties
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Melting point
185℃
density
1.471±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.
Store at +4°C
solubility
DMSO: ≥15mg/mL
form
Yellow solid
color
faint yellow to yellow
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3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Usage And Synthesis
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Biological Activity
Potent and competitive kynurenine 3-hydroxylase inhibitor (K i = 4.8 nM, IC 50 = 37 nM). Increases kynurenic acid levels to concentrations that antagonize the glycine site of NMDA receptors. Brain penetrant and exhibits antidystonic, anticonvulsant and neuroprotective activities.
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3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Preparation Products And Raw materials
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates:
Pharmaceutical intermediates;
OLED intermediates;
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