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CK-636
CK-636

CK-636

Price USD5.00
Packge 5KG
  • Min. Order:1KG
  • Supply Ability:1ton
  • Time:2019-09-04

Product Details

  • Product NameCK-636
  • CAS No.442632-72-6
  • EINECS No.200-256-5
  • MFC16H16N2OS
  • MW284.38
  • Appearancepowderpeach to light tan
  • storage temp. Keep in dark place,Sealed in dry,2-8°C
CK-636 Basic information
Product Name:
Synonyms:
CK-636;N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide;CK-0944636;CK-636 N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide;N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide CK636;CK-636, >=98%;CK-636(CK-0944636;442632-72-6
MF:
C16H16N2OS
MW:
284.37604
EINECS:
 
Product Categories:
Mol File:
CK-636 Structure
 
CK-636 Chemical Properties
storage temp. 
2-8°C
solubility 
DMSO: ≥20mg/mL
form 
powder
color 
peach to light tan
InChIKey
ACAKNPKRLPMONU-UHFFFAOYSA-N
CAS DataBase Reference
 
Safety Information
Hazard Codes 
Risk Statements 
WGK Germany 
3
MSDS Information
 
 
CK-636 Usage And Synthesis
CK-636 is an Arp2/3 complex inhibitor with IC50 of 4 μM, 24 μM and 32 μM for inhibition of actin polymerization induced by human, fission yeast and bovine Arp2/3 complex, respectively.
CK-636 inhibits actin polymerization mediated by Arp2/3 complex in live cells, and reduces the formation of actin filament comet tails by Listeria in infected SKOV3 cells. CK-636 inhibits lamellipodia formation at the leading edges of migrating T cells, and causes reduced velocity. In addition, a substantial fraction of CK-636-treated T cells on zigzag patterns with an acute turning angle are trapped near the interfaces formed by the turning points of zigzag patterns.
 

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;
  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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