Ridaforolimus
| Price | USD7.00 |
| Packge | 1KG |
- Min. Order:1KG
- Supply Ability:JD 427
- Time:2019-09-02
Product Details
- Product Name Ridaforolimus
- CAS No. 572924-54-0
- MFC53H84NO14P
- MW990.21
- AppearanceSolidOff-White to Pale Yellow
- Melting point 95-98°C
- storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere
- Boiling point 996.2±75.0 °C(Predicted)
- density 1.18±0.1 g/cm3(Predicted)
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Product Name:
Synonyms:
AP 23573, MK 8669, 42-DiMethylphosphinate-rapaMycin;RapaMycin,42-(diMethylphosphinate) (9CI);deforolimus 572924-54-0;572924-54-0;Deforolimus (AP23573)42-;Deforolimus, 98%, a potent and selective mTOR inhibitor;42-(Dimethylphosphinate)rapamycin;Deforolimus
CAS:
MF:
C53H84NO14P
MW:
990.214
EINECS:
Product Categories:
Mol File:
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Ridaforolimus Chemical Properties
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Melting point
95-98°C
storage temp.
Hygroscopic, -20?C Freezer, Under Inert Atmosphere
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Safety Information
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Ridaforolimus Usage And Synthesis
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Chemical Properties
Off-White Solid
Uses
An immunosupressant and is currently being investigated for use in cancer treatments. Ridaforolimus may act as a regulator of protein synthesis, cell proliferation, cell cycle progression and cell survival. Ridaforolimus, was formerly known as Deforolimus.
Uses
Ridaforolimus is a semisynthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group with a dimethylphosphinate moiety. Like all tacrolimus analogues, ridaforolimus binds to receptor protein, FKBP12. The complex then binds to mTOR preventing its interaction with target proteins. Ridaforolimus is extensively cited in the literature with over 70 citations.
Definition
ChEBI: A semisynthetic derivative that is sirolimus in which hydroxy group attached to the cyclohexyl moiety has been converted to the corresponding dimethylphosphinate.
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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