Amiloride hydrochloride
| Price | USD1.00 | USD2.00 |
| Packge | 1KG | 1KG |
- Min. Order:1KG
- Supply Ability:200kg
- Time:2019-09-02
Product Details
- Product NameAmiloride hydrochloride
- CAS No.2016-88-8
- EINECS No.217-958-2
- MFC6H8ClN7O.ClH
- MW266.09
- Appearancepowderyellow
- Melting point 293-294°C
- Water Solubility <0.1 g/100 mL at 19.5 ºC
- storage temp. Store at RT
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Product Name:
Synonyms:
amiloridechloride;amiprazidine;n-amidino-3,5-diamino-6-chloro-pyrazinecarboxamidmonohydrochloride;3,5-DIAMINO-N-(AMINOMETHYL)-6-CHLOROPYRAZINE CARBOXAMIDE HYDROCHLORIDE;HCL AMILORIDE HCL;N-amidino-3,5-diamino-6-chloropyrazinecarboxamide monohydrochloride;Amipramidin hydrochloride;Amipramizide hydrochloride
CAS:
MF:
C6H8ClN7O.ClH
MW:
266.09
EINECS:
217-958-2
Product Categories:
Mol File:
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Amiloride hydrochloride Chemical Properties
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Melting point
293-294°C
storage temp.
Store at RT
solubility
H2O: 50 mg/mL, clear, yellow-green
form
powder
color
yellow
Water Solubility
<0.1 g/100 mL at 19.5 ºC
CAS DataBase Reference
EPA Substance Registry System
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Safety Information
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Hazard Codes
Risk Statements
Safety Statements
RIDADR
UN 2811 6.1/PG 3
WGK Germany
3
RTECS
UQ2275500
HazardClass
6.1(a)
PackingGroup
II
HS Code
29339980
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Amiloride hydrochloride Usage And Synthesis
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Chemical Properties
Pale Yellow Solid
Uses
Na+ channel inhibitor, diuretic
Uses
A calcium channel andsodium channel protein inhibitor
Uses
Sodium channel blocker. Diuretic.
Definition
ChEBI: A hydrochloride obtained by combining amiloride with one molar equivalent of hydrochloric acid.
Brand name
Midamor (Merck).
General Description
Crystalline solid or very light yellow powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
A halogenated amine and amide, acidic salt. In aqueous solution, behaves as a weak acid. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Health Hazard
SYMPTOMS: Symptoms of exposure to Amiloride hydrochloride include headache, weakness, fatigue, back, chest, neck, shoulder or extremity pain; nausea, anorexia, vomiting, abdominal pain, hyperkalemia, paresthesias, shock, dizziness, coughing, shortness of breath, depression, nervousness, flaccid paralysis of the extremities, bradycardia, flatulence, skin rash, gas pain, constipation and dyspnea.
Fire Hazard
Flash point data for Amiloride hydrochloride are not available; however, Amiloride hydrochloride is probably combustible.
Biological Activity
Na + channel blocker. Defines the I 2A -amiloride sensitive and I 2B -amiloride insensitive imidazoline binding sites. Also inhibits TRPP3 channels.
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Amiloride hydrochloride Preparation Products And Raw materials
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Raw materials
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Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
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- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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