PD 0325901
| Price | USD3.00 |
| Packge | 1KG |
- Min. Order:3KG
- Supply Ability:1kg,5kg,100kg
- Time:2019-08-27
Product Details
- Product NamePD 0325901
- CAS No.391210-10-9
- EINECS No.687-152-7
- MFC16H14F3IN2O4
- MW482.19
- AppearanceWhite to off-white solidwhite to off-white
- storage temp. 2-8°C
- Melting point 112-114°C
- density 1.817±0.06 g/cm3(Predicted)
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Product Name:
Synonyms:
InSolution MEK1/2 Inhibitor III, PD0325901 - CAS 391210-10-9 - Calbiochem;MEK1/2 Inhibitor III - CAS 391210-10-9 - Calbiochem;PD0325901 (PD325901);PD-0235901;N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)aMino]be;PD325901;N-[(R)-2,3 -Dihydroxy-propoxy]-3,4-difluoro-2-(2-fluoro-4-iodo-phenylaMino)-benzaMide;N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide PD0325901
CAS:
MF:
C16H14F3IN2O4
MW:
482.191
EINECS:
687-152-7
Product Categories:
Mol File:
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PD 0325901 Chemical Properties
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Melting point
112-114°C
storage temp.
Store at -20°C
solubility
DMSO: soluble20mg/mL, clear
form
White to off-white solid
color
white to off-white
optical activity
[α]/D -1.8 to -3.5°, c = 1 mg/mL in methanol
InChIKey
SUDAHWBOROXANE-SECBINFHSA-N
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Safety Information
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Hazard Codes
Risk Statements
Safety Statements
RIDADR
UN 2811 6.1 / PGIII
WGK Germany
3
HazardClass
IRRITANT
HS Code
29242990
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PD 0325901 Usage And Synthesis
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Chemical Properties
White to Off-White Solid
Uses
The mitogenic extracellular kinase 1/2 (MEK1/2) inhibitor
Definition
ChEBI: A hydroxamic acid ester that is benzhydroxamic acid (N-hydroxybenzamide) in which the hydroxamic acid group has been converted to the corresponding 2,3-dihydroxypropyl ester and in which the benzene ring has been substituted at position by a (2-fluoro-4-iodophenyl)amino group and at positions 3 and 4 by fluorines (the R enantiomer).
Biological Activity
PD0325901 (PD325901) is selective and non ATP-competitive MEK inhibitor with an IC50 of 0.33 nM, roughly 500-fold more potent than CI-1040 on the phosphorylation of ERK1 and ERK2.
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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