Citicoline 987-78-0 CDP-choline CYTIDINE 5'-DIPHOSPHOCHOLINE 987-78-0

Product no. chemwillCDPC91055

 Citicoline 987-78-0 CDP-choline CYTIDINE 5'-DIPHOSPHOCHOLINE 987-78-0

 Citicoline CAS 987-78-0

CYTIDINE 5'-DIPHOSPHOCHOLINE CAS 987-78-0

CDP-choline CAS 987-78-0

Appearance & Physical State     White powder
Boiling Point     851.4ºC at 760 mmHg
Safety Info
HS Code     2942000000

Citicoline (INN), also known as cytidine diphosphate-choline (CDP-Choline) or cytidine 5'-diphosphocholine is a psychostimulant/nootropic. It is an intermediate in the generation of phosphatidylcholine from choline.
Studies suggest that CDP-choline supplements increase dopamine receptor densities, and suggest that CDP-choline supplementation helps prevent memory impairment resulting from poor environmental conditions. Preliminary research has found that citicoline supplements help improve focus and mental energy and may possibly be useful in the treatment of attention deficit disorder.
Citicoline has also been shown to elevate ACTH independently from CRH levels and to amplify the release of other HPA axis hormones such as LH, FSH, GH and TSH in response to hypothalamic releasing factors. These effects on HPA hormone levels may be beneficial for some individuals but may have undesirable effects in those with medical conditions featuring ACTH or cortisol hypersecretion including PCOS, type II diabetes and major depressive disorder.

Name         Citicoline
Synonyms         Cytidine 5'-diphosphate choline; Cytidine 5'-diphosphocholine; Cytidine choline diphosphate; Cytidine diphosphate choline; Cytidine diphosphate choline ester; Cytidine diphosphocholine; Cytidine diphosphorylcholine; Cytidine 5'-(trihydrogen diphosphate) P'-[2-(trimethylammonio)ethyl] ester inner salt; Cytidoline
Cytidine Diphosphate Choline; Citicolina; 5'-O-[hydroxy({[2-(trimethylammonio)ethoxy]phosphinato}oxy)phosphoryl]cytidine; Cytidine 5'-Diphosphocholine

Molecular Formula         C14H26N4O11P2
Molecular Weight         488.32
CAS Registry Number         987-78-0
EINECS         213-580-7

Product Name:    CYTIDINE 5'-DIPHOSPHOCHOLINE
Synonyms:    Citifar;Corenalin;Cyscholin;Cytidine 5'-(cholinyl pyrophosphate);Cytidine 5'-(trihydrogen diphosphate), P'-[2-(trimethylammonio)ethyl] ester, hydroxide, inner salt;Dierucoyl Phosphoethanolamine;2-(((((((2R,3S,4R,5R)-5-(4-aMino-2-oxopyriMidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)Methoxy)(hydroxy)phosphoryl)oxy)oxidophosphoryl)oxy)-N,N,N-triMethylethanaMiniuM;CYTIDINE-5'-DIPHOSPHOCHOLINE(P)
CAS:    987-78-0
MF:    C14H26N4O11P2
MW:    488.32
EINECS:    213-580-7

CYTIDINE 5'-DIPHOSPHOCHOLINE Usage And Synthesis
Uses    antidepressant, 5HT uptake inhibitor
CYTIDINE 5'-DIPHOSPHOCHOLINE Preparation Products And Raw materials
Raw materials    Iodomethane-->Ethyleneimine-->Yeast extract-->Cytosine-->phosphorylcholine