N,N-Dimethylpyridin-4-amine DMAP 4-Dimethylaminopyridine 1122-58-3 In stock

Product no. chemwill4DPE1002

 4-Dimethylaminopyridine (DMAP) is a derivative of pyridine with the chemical formula (CH3)2NC5H4N. This colourless solid is of interest because it is more basic than pyridine, owing to the resonance stabilisation from the NMe2 substituent.
Because of its basicity, DMAP is a useful nucleophilic catalyst for a variety of reactions such as esterifications with anhydrides, the Baylis-Hillman reaction, hydrosilylations, tritylation, the Steglich rearrangement, Staudinger synthesis of β-lactams and many more. Chiral DMAP analogues are used in kinetic resolution experiments of mainly secondary alcohols and Evans auxiliary type amides.
Basic Info
Chemical Name     4-Dimethylaminopyridine
Synonyms     

4-Dimethylaminopyrid; AURORA KA-6495; N-(4-Pyridyl)dimethylamine; 4-Pyridinamine, N,N-dimethyl-; 4-Dimethylaminepyridine; Expand
CAS No.     1122-58-3
Molecular Formula     C7H10N2
Molecular Weight     122.16800
PSA     16.13000
LogP     1.14760
Properties
Appearance & Physical State     white to yellow crystalline powder
Density     1.012 g/cm3
Boiling Point     162ºC (50 mmHg)
Melting Point     108-113ºC
Flash Point     110ºC
Refractive Index     n20/D 1.431
Water Solubility     76 g/L (25 ºC)
Stability     Stable. Incompatible with acids, oxidizing agents.
Storage Condition     Store in dark
Vapor Pressure     0.431mmHg at 25°C
Safety Info
RTECS     US8400000
Hazard Class     8
Safety Statements     S26-S28-S36/37/39-S45
HS Code     2933399090
WGK Germany     3
Packing Group     II
RIDADR     UN 1760/2811
Risk Statements     R24/25; R34
Hazard Codes     T
Symbol     GHS06, GHS08
Hazard Declaration     H302; H311; H315; H319; H335; H351
Caution Statement     P280; P301 + P312 + P330; P302 + P352 + P312; P304 + P340 + P312; P305 + P351 + P338; P337 + P313
Signal Word     Danger