Cinobufagin
| Price | USD1.00 |
| Packge | 1KG |
- Min. Order:1g
- Supply Ability:100KG
- Time:2019-07-06
Product Details
- Product NameCinobufagin
- CAS No.470-37-1
- EINECS No.636-927-8
- MFC26H34O6
- MW442.55
- InChIKeySCULJPGYOQQXTK-QZXYOKJUNA-N
- Appearancepowder to crystalWhite to Light yellow
- Melting point 133 °C(lit.)
- storage temp. 2-8°C
- Boiling point 300 °C(lit.)
- density 1.261 g/cm3
| Cinobufagin Basic information |
| Product Name: | Cinobufagin |
| Synonyms: | RARECHEM BK HC T302;TRANS-3-PHENYLPROPENOIC ACID;TRANS-3-BENZENEPROPENOIC ACID;TRANS-CINNAMYLIC ACID;16-beta)-bet;22-dienolide,16-(acetyloxy)-14,15-epoxy-3-hydroxy-,(3-beta,5-beta,15-bufa-2;cinobufagine;AKOS B004228 |
| CAS: | 470-37-1 |
| MF: | C26H34O6 |
| MW: | 442.55 |
| EINECS: | 205-398-1 |
| Product Categories: | Steroids;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract |
| Mol File: | 470-37-1.mol |
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| Cinobufagin Chemical Properties |
| Melting point | 133 °C(lit.) |
| Boiling point | 300 °C(lit.) |
| Fp | >230 °F |
| storage temp. | 2-8°C |
| Safety Information |
| Hazard Codes | Xi,T+,Xn |
| Risk Statements | 36/37/38-26/27/28-42/43-20/22 |
| Safety Statements | 26-36-45-36/37/39-22-24/25 |
| RIDADR | UN 2811 6.1/PG 1 |
| WGK Germany | 3 |
| RTECS | GD7850000 |
| HazardClass | 6.1(a) |
| PackingGroup | II |
| HS Code | 29322090 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| Cinobufagin Usage And Synthesis |
| Description | Cinobufagin is a cardiotoxic bufanolide steroid secreted by the Asiatic toad Bufo gargarizans, having similar effects to digitalis and used in traditional Chinese medicine. It has potential antineoplastic activity and now is widely used in clinical practice, especially in anti-liver cancer. It has benn found to suppress cancer cell proliferation and cause apoptosis in cancer cells via a sequence of apoptotic modulators, including mitochondrial Bax and cytosolic chromosome c, and caspases 3, 8, and 9. |
| References | 1. https://en.wikipedia.org/wiki/Cinobufagin 2. https://www.cancer.gov/publications/dictionaries/cancer-drug?cdrid=689412 3. http://www.yourdictionary.com/cinobufagin 4. https://www.medchemexpress.com/cinobufagin.html |
| Uses | Cinobufagine is a major component of cinobufacini (huachansu), is an important cardenolidal steroid. Cinobufagine was show |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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