CYTOCHALASIN D
| Price | USD1.00 |
| Packge | 1kg |
- Min. Order:1g
- Supply Ability:100KG
- Time:2019-07-06
Product Details
- Product NameCYTOCHALASIN D
- CAS No. 22144-77-0
- EINECS No.244-804-1
- MFC30H37NO6
- MW507.62
- InChIKeySDZRWUKZFQQKKV-JHADDHBZSA-N
- AppearanceWhite solidWhite
- Melting point 255-260°C
- storage temp. −20°C
- Boiling point 595.84°C (rough estimate)
- density 1.1764 (rough estimate)
| CYTOCHALASIN D Basic information |
| Product Name: | CYTOCHALASIN D |
| Synonyms: | ZYGOSPORIN A;CYTOCHALASIN D;CYTOCHALASIN D, ZYGOSPORIUM MANSONII;CYTOCHALASIN D, ZYGUSPORIUM MANSONII;(7S,13E,16S,18R,19E,21R)-21-(ACETYLOXY)-7,18-DIHYDROXY-16,18-DIMETHYL-10-PHENYL[11]CYTOCHALASA-6(12),13,19-TRIENE-1,17-DIONE;(11)cytochalasa-6(12),13,19-triene-1,17-dione,21-(acetyloxy)-7,18-dihydroxy-16;,12,15-decahydro-6,12,15-trihydroxy-4,10,12-trimethyl-5-methylene-,15-acetate;,18-dimethyl-10-phenyl-,(7s,13e,16s,18r,19e,21r)- |
| CAS: | 22144-77-0 |
| MF: | C30H37NO6 |
| MW: | 507.62 |
| EINECS: | 244-804-1 |
| Product Categories: | Caspases/Apoptosis;antibiotic |
| Mol File: | 22144-77-0.mol |
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| CYTOCHALASIN D Chemical Properties |
| Melting point | 255-260°C |
| Boiling point | 595.84°C (rough estimate) |
| density | 1.1764 (rough estimate) |
| refractive index | 1.6310 (estimate) |
| Fp | 87℃ |
| storage temp. | −20°C |
| solubility | DMSO: soluble |
| Safety Information |
| Hazard Codes | T |
| Risk Statements | 25-63 |
| Safety Statements | 36/37-45 |
| RIDADR | UN 1544 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | GZ4850000 |
| HazardClass | 6.1(a) |
| PackingGroup | I |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| CYTOCHALASIN D Usage And Synthesis |
| Chemical Properties | Powder |
| Uses | Cytochalasin D acts as an anti-hypertensive drug acting on human intestinal epithelial caco-2 cells. Also has activity in HMG-CoA reductase inhibitors used in the lowering of cholesterol. Actin inhib itor, actin polymerization inhibitor affecting cell movement, growth, phagocytosis and even secretion. |
| Uses | Cytochalasin D is the most studied of the cytochalasins. Like most of the members of this mycotoxin class, cytochalasin D exhibits potent inhibition of actin filament function leading to cell death by apoptosis. This led to early investigation of the metabolite as an antitumour agent. Cytochalasin D has become one of the standard cellular probes for investigating the role of actin in cell biology. |
| Uses | Cytochalasin D is the most studied of the cytochalasins. Like most of the members of this mycotoxin class, cytochalasin D exhibits potent inhibition of actin filament function leading to cell death by apoptosis. This led to early investigation of the metabolite as an antitumor agent. Cytochalasin D has become one of the standard cellular probes for investigating the role of actin in cell biology. |
| Uses | A cell cycle arresting compound used in actin polymerization studies and cytological research |
| Definition | ChEBI: An organic heterotricyclic compound that is a mycotoxin produced by Helminthosporium and other moulds which is cell permeable and a potent inhibitor of actin polymerisation and DNA synthesis. |
| General Description | Needles or fluffy white powder. |
| Reactivity Profile | CYTOCHALASIN D may be sensitive to exposure to heat. CYTOCHALASIN D can react with strong oxidizing agents, strong acids and strong bases. . |
| Fire Hazard | Flash point data for CYTOCHALASIN D are not available; however, CYTOCHALASIN D is probably combustible. |
| Biological Activity | Potent disruptor of actin filament function. Alters tight junction permeability. Unlike cytochalasin B, does not inhibit monosaccharide transport across the plasma membrane. |
| Safety Profile | Poison by ingestion, subcutaneous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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