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HomecompanyIrinotecan hydrochloride
Irinotecan hydrochloride
Irinotecan hydrochloride

Irinotecan hydrochloride

Price USD1.00
Packge 1kg
  • Min. Order:1g
  • Supply Ability:100KG
  • Time:2019-07-06

Product Details

  • Product NameIrinotecan hydrochloride
  • CAS No. 100286-90-6
  • EINECS No.600-054-0
  • MFC33H39ClN4O6
  • MW623.15
  • AppearanceYellow powderWhite to yellow
  • Melting point 250-256°C (dec.)
  • Boiling point 257 °C
  • storage temp. 2-8°C
  • Water Solubility Soluble in DMSO at 100mg/ml. Soluble in water at 25mg/ml with warming
Irinotecan hydrochloride Basic information
Product Name: Irinotecan hydrochloride
Synonyms: Camptothecin II;CPT-II;[1,4′-Bipiperidine]-1′-carboxylic acid, CPT-11,(S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl ester;(4S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylicacidesterhydrochloride;(S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl ester;Irinotecan hydrochloride(CPT-11);Irinotecan HCI;Irinotecan-D10 HCl
CAS: 100286-90-6
MF: C33H39ClN4O6
MW: 623.14
EINECS: 1308068-626-2
Product Categories: API;Anti-cancer&immunity;Active Pharmaceutical Ingredients;Antineoplastic;Antitumors for Research and Experimental Use;Biochemistry;Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Irinotecan
Mol File: 100286-90-6.mol
Irinotecan hydrochloride Structure
 
Irinotecan hydrochloride Chemical Properties
Melting point  250-256°C (dec.)
Boiling point  257 °C
refractive index  67.7 ° (C=1, H2O)
storage temp.  Refrigerator
solubility  Soluble in DMSO or DMF at approximately 20mg/ml. Sparingly soluble in aqueous buffers. /n
Water Solubility  Soluble in DMSO at 100mg/ml. Soluble in water at 25mg/ml with warming
Merck  5091
CAS DataBase Reference 100286-90-6(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xn
Risk Statements  22
RTECS  DW1060750
MSDS Information
 
 
Irinotecan hydrochloride Usage And Synthesis
Chemical Properties Yellow Crystalline Powder
Uses antineoplactic;'inhibitor of topoisomerase I
Uses A DNA topoisomerase inhibitor
Definition ChEBI: A hydrochloride obtained by combining irinotecan with one molar equivalent of hydrochloric acid. Used (in the form of its trihydrate) in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancr as after disease progression following gemcitabine-based therapy. It is converted via hydrolysis of the carbamate linkage to its active metabolite, SN-38, which is ~1000 times more active.
Brand name Camptosar (Pharmacia &Upjohn) .
Biological Activity Inhibitor of DNA topoisomerase I that displays antitumor activity against a range of tumor types.

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 

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career henan chemical co

Henan China
  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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