NVP-LDE225
| Price | USD2.00 |
| Packge | 1kg |
- Min. Order:1kg
- Supply Ability:100kg
- Time:2019-07-06
Product Details
- Product NameNVP-LDE225
- CAS No.956697-53-3
- EINECS No.1312995-182-4
- MFC26H26F3N3O3
- MW485.5
- AppearanceWhite solid.Light Purple
- density 1.255
- Boiling point 544.5±50.0 °C(Predicted)
- Melting point 154-157°C
- storage temp. Refrigerator
| NVP-LDE225 Basic information |
| Product Name: | NVP-LDE225 |
| Synonyms: | NVP-LDE225;LDE225;Erismodegib;rel-N-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxamide;LDE225 (NVP-LDE225);[1,1'-Biphenyl]-3-carboxaMide, N-[6-[(2R,6S)-2,6-diMethyl-4-Morpholinyl]-3-pyridinyl]-2-Methyl-4'-(trifluoroMethoxy)-, rel-;NVP-LDE225(LDE225,ErisModegib);LDE225 (NVP-LDE225,ErisModegib) |
| CAS: | 956697-53-3 |
| MF: | C26H26F3N3O3 |
| MW: | 485.4981496 |
| EINECS: | 1312995-182-4 |
| Product Categories: | Aromatics;Chiral Reagents;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol File: | 956697-53-3.mol |
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| NVP-LDE225 Chemical Properties |
| density | 1.255 |
| Safety Information |
| NVP-LDE225 Usage And Synthesis |
| Uses | A potent, selective and orally bioavailable Smoothened (SMO) antagonist; it inhibits hedgehog (Hh) signaling pathway via antagonism of the Smoothened receptor (SMO). Antineoplastic. |
| Definition | ChEBI: A member of the classo of biphenyls that is the amide obtained by formal condensation of the carboxy group of 2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxylic acid with the amino group of 6-(2,6-dimethylmorpholin-4-yl)pyridin-3-amine. Used (as it phosphate salt) for treatment of locally advanced basal cell carcinoma. |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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