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o-Cresol
o-Cresol

o-Cresol

Price USD1.00
Packge 1kg
  • Min. Order:1g
  • Supply Ability:100KG
  • Time:2019-07-06

Product Details

  • Product Nameo-Cresol
  • CAS No. 95-48-7
  • EINECS No.202-423-8
  • MFC7H8O
  • MW108.14
  • InChIKeyQWVGKYWNOKOFNN-UHFFFAOYSA-N
  • AppearanceLiquid or Low Melting Solidwhite to brown
  • Water Solubility 20 g/L (20 ºC)
  • storage temp. under inert gas
  • density 1.048 g/mL at 25 °C
  • Boiling point 191 °C (lit.)
  • Melting point 29-31 °C (lit.)
o-Cresol Basic information
Product Name: o-Cresol
Synonyms: O-CRESOL;O-CRESYLIC ACID;O-METHYLPHENOL;O-HYDROXYTOLUENE;FEMA 3480;2-HYDROXYTOLUENE;2-METHYLPHENOL;1-HYDROXY-2-METHYLBENZENE
CAS: 95-48-7
MF: C7H8O
MW: 108.14
EINECS: 202-423-8
Product Categories: alcohol
Mol File: 95-48-7.mol
o-Cresol Structure
 
o-Cresol Chemical Properties
Melting point  30-34 °C
Boiling point  191 °C
density  1.048 g/mL at 25 °C
vapor density  3.72 (vs air)
vapor pressure  0.3 mm Hg ( 20 °C)
refractive index  1.5361
FEMA  3480 | O-CRESOL
Fp  178 °F
storage temp.  2-8°C
solubility  20g/l
form  Liquid or Low Melting Solid
pka 10.2(at 25℃)
color  white to brown
PH 4.8 (20g/l, H2O, 20℃)
explosive limit 1.47%, 148°F
Water Solubility  20 g/L (20 ºC)
Merck  14,2579
BRN  506917
Stability: Stable, but light and air sensitive. Combustible. Incompatible with oxidizing agents, bases.
CAS DataBase Reference 95-48-7(CAS DataBase Reference)
NIST Chemistry Reference Phenol, 2-methyl-(95-48-7)
EPA Substance Registry System Phenol, 2-methyl-(95-48-7)
 
Safety Information
Hazard Codes  T
Risk Statements  24/25-34-39/23/24/25-23/24/25
Safety Statements  36/37/39-45-36/37
RIDADR  UN 3455 6.1/PG 2
WGK Germany  1
RTECS  GO6300000
8-23
TSCA  Yes
HazardClass  6.1
PackingGroup  II
HS Code  29071200
Hazardous Substances Data 95-48-7(Hazardous Substances Data)
Toxicity LD50 orally in rats: 1.35 g/kg (Deichmann, Witherup)
MSDS Information
Provider Language
2-Hydroxytoluene English
SigmaAldrich English
ACROS English
ALFA English
 
o-Cresol Usage And Synthesis
Chemical Properties colourless to light yellow liquid
Definition ChEBI: A cresol that is phenol substituted by a methyl group at position 2. It is a minor urinary metabolite of toluene.
General Description Colorless or yellow to brown-yellow or pinkish colored liquid with a phenol-like odor. Toxic by ingestion and/or skin absorption. May have a flash point between 100 and 199°F. Causes burns to skin, eyes and mucous membranes. Insoluble in water.
Air & Water Reactions Sensitive to light and air. Insoluble in water.
Reactivity Profile o-Cresol is incompatible with oxidizing agents and bases. Mixing o-Cresol with chlorosulfonic acid, nitric acid and oleum in a closed contained caused the temperature and pressure to increase.
Health Hazard The chemical is rated as a very toxic compound with a probable oral lethal dose in humans of 50-500 mg/kg, or between 1 teaspoon and 1 ounce for a 70 kg (150 lb.) person. It is a strong dermal irritant and frequently causes dermatitis. Serious or fatal poisoning may result if large areas of skin are wet with cresol, o- and the substance is not removed immediately. Ingestion of even a small amount may cause paralysis and coma. It is corrosive to body tissues, with toxicity similar to phenol.
Fire Hazard Fire may produce irritating or poisonous gases. Runoff from fire control water may give off poisonous gases. o-Cresol may burn but does not ignite readily. Container may explode in heat of fire. Slight explosion and fire hazard in the form of vapor when exposed to heat or flame. When heated to decomposition, o-Cresol emits highly toxic fumes. Reacts violently with nitric acid, oleum, and chlorosulfonic acid. Hazardous polymerization may not occur.
Safety Profile Poison by ingestion, inhalation, subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by skin contact. A severe eye and skin irritant. Human mutation data reported. Questionable carcinogen with experimental neoplastigenic data. Flammable when exposed to heat, flame, or oxidants. To fight fire, water may be used to blanket fire; foam, fog, mist, dry chemical. See also other cresol entries and PHENOL.
Purification Methods It can be freed from m-and p-isomers by repeated fractional distillation, It crystallises from *benzene by addition of pet ether. It has been fractionallly crystallised by partial freezing of its melt. The 3,5-dinitrobenzoate (prepared with 3,5-dinitrobenzoyl chloride in dry pyridine, and recrystallised from EtOH or aqueous Me2CO) has m 138o. [Beilstein 6 IV 1940.]

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 

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  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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