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Homecompany Ciprofibrate
	Ciprofibrate
	Ciprofibrate

Ciprofibrate

Price USD1.00
Packge 1kg
  • Min. Order:1g
  • Supply Ability:100KG
  • Time:2019-07-06

Product Details

  • Product Name Ciprofibrate
  • CAS No.52214-84-3
  • EINECS No.257-744-6
  • MFC13H14Cl2O3
  • MW289.15
  • AppearanceneatWhite to Pale Beige
  • storage temp. 2-8°C
  • Melting point 114-116°
  • Boiling point 401.74°C (rough estimate)
  • density 1.2576 (rough estimate)
Ciprofibrate Basic information
Product Name: Ciprofibrate
Synonyms: 2-(p-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropionicacid;2-[4-(2,2-Dichlom-cyclopropyl)phenoxy]-2-methy|propanoic acid;Cipml;Lipanor;Modalim;Win-35833;2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropionic acid;Ciprofibric acid
CAS: 52214-84-3
MF: C13H14Cl2O3
MW: 289.15
EINECS: 257-744-6
Product Categories: Intracellular receptor;API
Mol File: 52214-84-3.mol
Ciprofibrate Structure
 
Ciprofibrate Chemical Properties
Melting point  114-116°
Boiling point  401.74°C (rough estimate)
density  1.2576 (rough estimate)
refractive index  1.5209 (estimate)
storage temp.  2-8°C
solubility  Practically insoluble in water, freely soluble in anhydrous ethanol, soluble in toluene.
Merck  14,2313
CAS DataBase Reference 52214-84-3(CAS DataBase Reference)
 
Safety Information
Hazard Codes  T
Risk Statements  45
Safety Statements  53-22-36/37/39-45
WGK Germany  3
RTECS  UF0880000
MSDS Information
Provider Language
Ciprofibrate English
SigmaAldrich English
 
Ciprofibrate Usage And Synthesis
Chemical Properties Off-White to Pale Beige Solid
Uses Ciprofibrate is a hypolipemic agent, related structurally to Clofibrate (C586910). Ciprofibrate is used as an antilipemic.
Uses antihyperlipidemic
Uses Peroxisome proliferator-activated receptor α (PPARα) is a ligand-activated transcription factor involved in the regulation of lipid homeostasis. Activation of PPARα results in expression of a variety of genes, particularly those involved in fatty acid β-oxidation, binding, and transport. Ciprofibrate activates PPARα with an EC50 value of 20 μM and only marginally affects PPARγ (EC50 = >300 μM). It has been shown to lower adipose tissue weight and reduce plasma insulin concentrations in obese rats and has been used clinically in the treatment of dyslipidemia. Ciprofibrate reportedly stimulates cholesteryl ester transfer protein expression and improves the flow of cholesterol through the indirect reverse cholesterol transport system, preserving plasma HDL.

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 

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  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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