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Clonidine hydrochloride
Clonidine hydrochloride

Clonidine hydrochloride

Price USD1.00
Packge 1kg
  • Min. Order:1g
  • Supply Ability:100KG
  • Time:2019-07-06

Product Details

  • Product NameClonidine hydrochloride
  • CAS No.4205-91-8
  • EINECS No.224-121-5
  • MFC9H10Cl3N3
  • MW266.55
  • InChIKeyZNIFSRGNXRYGHF-UHFFFAOYSA-N
  • Appearancesolidwhite
  • Melting point 312 °C
  • storage temp. 2-8°C
  • Water Solubility Soluble in water (50 mg/ml), DMSO (75 mM), methanol, chloroform (slightly), and dehydrated alcohol.
Clonidine hydrochloride Basic information
Product Name: Clonidine hydrochloride
Synonyms: TIMTEC-BB SBB003065;CLONIDINE HCL;CLONIDINE HYDROCHLORIDE;DIXARIT;2-[2,6-DICHLOROANILINE]-2-IMIDAZOLINE HYDROCHLORIDE;2-(2,6-DICHLOROANILINO)-2-IMIDAZOLINE, HCL;2-(2,6-DICHLOROANILINO)-2-IMIDAZOLINE HYDROCHLORIDE;2-(2,6-DICHLOROPHENYLAMINO)-2-IMIDAZOLINE HYDROCHLORIDE
CAS: 4205-91-8
MF: C9H10Cl3N3
MW: 266.55
EINECS: 224-121-5
Product Categories: Adrenoceptor;Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;CATAPRES;Other APIs
Mol File: 4205-91-8.mol
Clonidine hydrochloride Structure
 
Clonidine hydrochloride Chemical Properties
Melting point  312 °C
storage temp.  2-8°C
solubility  H2O: 50 mg/mL, clear, colorless
color  white
Water Solubility  Soluble in water (50 mg/ml), DMSO (75 mM), methanol, chloroform (slightly), and dehydrated alcohol.
Merck  14,2390
InChIKey GLEWMLFXCSBZLK-UHFFFAOYSA-N
CAS DataBase Reference 4205-91-8(CAS DataBase Reference)
 
Safety Information
Hazard Codes  T+
Risk Statements  25-26
Safety Statements  22-26-28-36/37/39-45
RIDADR  UN 2811 6.1/PG 1
WGK Germany  3
RTECS  NJ2490000
10
HazardClass  6.1(b)
PackingGroup  III
Toxicity LD50 in mice, rats (mg/kg): 328, 270 orally; 18, 29 i.v. (Walland)
MSDS Information
Provider Language
SigmaAldrich English
 
Clonidine hydrochloride Usage And Synthesis
Chemical Properties White Solid
Uses Labelled Clonidine. α2-Adrenergic agonist. Antihypertensive; analgesic for neuropathic pain.
Uses `a2-adrenoceptor agonist, imidazoline receptor ligand, anti-hypertensive
Uses In shaving soaps.
Brand name Catapres (Boehrin- ger Ingelheim); Duraclon (Xanodyne).
Biological Activity Prototypical I 1 imidazoline receptor ligand. α 2 -adrenergic receptor agonist. Antihypertensive.
Purification Methods This antihypertensive is recrystallised from EtOH/Et2O and dried in a vacuum (solubility in H2O is 5%). The free base has m 124-125o and is recrystallised from hexane. [Jen et al. J Med Chem 18 90 1975, NMR: Jackman & Jen J Am Chem Soc 97 2811 1975.]

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 
  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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