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Homecompany Meloxicam
Meloxicam
Meloxicam

Meloxicam

Price USD1.00
Packge 1kg
  • Min. Order:1g
  • Supply Ability:100KG
  • Time:2019-07-06

Product Details

  • Product Name Meloxicam
  • CAS No. 71125-38-7
  • EINECS No.615-253-8
  • MFC14H13N3O4S2
  • MW351.4
  • AppearanceOff-white solidyellow
  • Melting point 255 °C
  • storage temp. 2-8°C
  • Water Solubility practically insoluble in water(0.154 mg/mL), with higher solubility observed in strong acids and bases.
  • density 1.613±0.06 g/cm3(Predicted)
Product Name: Meloxicam
Synonyms: MeloxicamUsp27;4-Hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazin-3-crboxamide 1,1-dioxide;MeloxicaM, BP;Meloxicam (400 mg);MeloxicaM API;MeloxicaM (Mobic);4-Hydroxy-2-Methyl-N-(5-Methylthiazol-2-yl)-2H-benzo[e][1,2]thiazine-3-carboxaMide 1,1-dioxide;4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-1,1-dioxide-2H-1,2-benzothiazine-3-carboxamide
CAS: 71125-38-7
MF: C14H13N3O4S2
MW: 351.4
EINECS: 2017-001-1
Product Categories: Lipid signaling;AVAPRO;Other APIs;Active Pharmaceutical Ingredients;API;Health & Beauty;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;API's
Mol File: 71125-38-7.mol
Meloxicam Structure
 
Meloxicam Chemical Properties
Melting point  255 °C
storage temp.  0-6°C
solubility  DMSO: soluble
pka 4.08 in water; 4.24 ± 0.01 in water/ethanol (1:1); 4.63 ± 0.03 in water/ethanol (1:4)
color  yellow
Water Solubility  Soluble in water (22 mg/ml), DMSO (25 mg/ml), DMF, acetone(slightly soluble), ethanol(slightly soluble), and methanol(slightly soluble).
Merck  14,5826
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey ZRVUJXDFFKFLMG-UHFFFAOYSA-N
 
Safety Information
Hazard Codes  Xn,T
Risk Statements  22-36/37/38-25
Safety Statements  26-45-60-36/37
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  DL0702000
HazardClass  6.1
PackingGroup  III
HS Code  29349990
Toxicity LD50 orally in mice: 470 mg/kg (Trummlitz, 1980)
MSDS Information
Provider Language
Meloxicam English
 
Meloxicam Usage And Synthesis
Description Known as a nonsteroidal anti-inflammatory drug (NSAID), Meloxicam is commonly used to treat pain or inflammation caused by rheumatoid arthritis and osteoarthritis in adults. It is also used to treat juvenile rheumatoid arthritis in children who are at least 2 years old. It is effective to reduce pain, inflammation, swelling, and stiffness of the joints. Developed by Boehringer-Ingelheim, Meloxicam is a derivative of oxicam that can relieve the symptoms of arthritis, primary dysmenorrhea, fever with analgesic and antipyretic properties. Meloxicam was approved for use in April 2000.
Anti-inflammatory effects of meloxicam function by inhibiting the prostaglandin synthetase (cyclooxygenase 1 and 2) which results in a decrease of the synthesis of prostaglandins. As prostaglandins are chemicals that contribute to inflammation especially within joints, which leads to the common symptoms of pain, tenderness, and swelling associated with arthritis, inhibition of their synthesis can be associated with the analgesic and antipyretic effects of meloxicam. As a result, inflammation and its accompanying symptoms are reduced. Meloxicam starts to relieve pain about 30 to 60 minutes after administration.
References https://en.wikipedia.org/wiki/Meloxicam 
https://www.drugbank.ca/drugs/DB00814
https://www.drugs.com/meloxicam.html
http://www.medicinenet.com/meloxicam/article.htm
Chemical Properties Light Yellow Solid
Uses Preferential cyclooxygenase (COX-2) inhibitor. Sudoxicam and Meloxicam are nonsteroidal anti-inflammatory drugs (NSAIDs) from the enol-carboxamide class.
Uses angiotensin 2 receptor antagonist
Uses For symptomatic treatment of arthritis and osteoarthritis.
Uses An inhibitor of Cox-1 and Cox-2, selective for Cox-2.
Uses Preferential cyclooxygenase (COX-2) inhibitor. Used as an anti-inflammatory.
Definition ChEBI: A benzothiazine that is piroxicam in which the pyridin-2-yl group is replaced by a 5-methyl-1,3-thiazol-2-yl group. A non-steroidal anti-inflammatory drug and selective inhibitor of COX-2, it is used particularly for the management of rheumatoid arthritis.
Brand name Mobic (Boehringer Ingelheim).

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 

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career henan chemical co

Henan China
  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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