Sotalol hydrochloride
| Price | USD1.00 |
| Packge | 1kg |
- Min. Order:1g
- Supply Ability:100KG
- Time:2019-07-06
Product Details
- Product NameSotalol hydrochloride
- CAS No. 959-24-0
- EINECS No.213-496-0
- MFC12H21ClN2O3S
- MW308.82
- Appearancepowderwhite to off-white
- Melting point 218-220°C
- storage temp. 2-8°C
- Water Solubility Soluble in phosphate buffered saline, DMSO, ethanol, water, and methanol.
| Sotalol hydrochloride Basic information |
| Product Name: | Sotalol hydrochloride |
| Synonyms: | 4-(2-isopropylamino-1-hydroxyaethyl)methanesulfonailidhydrochlorid;4’-(1-hydroxy-2-(isopropylamino)ethyl)methanesulfonanilidemonohydrochloride;4’-(1-hydroxy-2-(isopropylamino)ethyl)-methanesulfonanilidmonohydrochlorid;isopropylaminohydroxyethylmethanesulfonanilidehydrochloride;meadjohnson1999;n-isopropyl-beta-(4-methanesulfonamidophenyl)ethanolaminehydrochloride;4'-(1-hydroxy-2-isopropylaminoethyl)methanesulphonanilide hydrochloride;BETAPACE |
| CAS: | 959-24-0 |
| MF: | C12H21ClN2O3S |
| MW: | 308.82 |
| EINECS: | 213-496-0 |
| Product Categories: | Miscellaneous Natural Products;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Adrenoceptor;Amines;Aromatics;Sulfur & Selenium Compounds;EXCENEL |
| Mol File: | 959-24-0.mol |
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| Sotalol hydrochloride Chemical Properties |
| Melting point | 218-220°C |
| storage temp. | Store at RT |
| solubility | H2O: 20 mg/mL |
| form | powder |
| color | white to off-white |
| Water Solubility | Soluble in phosphate buffered saline, DMSO, ethanol, water, and methanol. |
| CAS DataBase Reference | 959-24-0(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| RTECS | PB0826000 |
| Toxicity | LD50 in male mice, rats (mg/kg): 2600, 3450 orally; 670, 680 i.p.; LD50 orally in rabbits: 1000 mg/kg; LD50 i.p. in dogs: 330 mg/kg (Lish) |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| Sotalol hydrochloride Usage And Synthesis |
| Chemical Properties | White Crystalline Solid |
| Uses | A potent -adrenergic receptor antagonist. A class III antiarrythmic. It has been shown to prolong action potential and increases the refractory period |
| Uses | A potent α-adrenergic receptor antagonist. A class III antiarrythmic. It has been shown to prolong action potential and increases the refractory period. |
| Uses | antibacterial |
| Definition | ChEBI: A hydrochloride salt that is the monohydrochloride of sotalol. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias. |
| Brand name | Betapace(Berlex); Sorine (Upsher Smith). |
| Biological Activity | A relatively potent pure β adrenergic antagonist, unique in possessing additional class III antiarrhythmic activity. Also available as part of the Mixed Adrenergic Tocriset™ . |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
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- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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