D-ERYTHRO-SPHINGOSINE
Price | USD1.00 |
Packge | 1kg |
- Min. Order:1g
- Supply Ability:100KG
- Time:2019-07-06
Product Details
- Product NameD-ERYTHRO-SPHINGOSINE
- CAS No.123-78-4
- EINECS No.204-651-3
- MFC18H37NO2
- MW299.49
- AppearancePowder or Waxy SolidWhite to cream
- storage temp. -20°C
- Melting point 74.2-78.1 °C
- Boiling point 440.8°C (rough estimate)
- density 0.9758 (rough estimate)
D-ERYTHRO-SPHINGOSINE Basic information |
Product Name: | D-ERYTHRO-SPHINGOSINE |
Synonyms: | SPHINGOSINE;SPHINGOSINE, C18 CHAIN;SPHINGOSINE, D-ERYTHRO;TRANS D-THREO-SPHINGOSINE;TRANS D-ERYTHRO-SPHINGOSINE;TRANS-D-ERYTHRO-2-AMINO-4-OCTADECENE-1,3-DIOL;BRAIN SPHINGOSINE;BRAIN, BOVINE |
CAS: | 123-78-4 |
MF: | C18H37NO2 |
MW: | 299.49 |
EINECS: | 204-651-3 |
Product Categories: | Mixed Fatty Acids;Fatty Acid Derivatives & Lipids;Glycerols;Inhibitors;Protein Kinase Inhibitors and Activators;Protein Kinase;Amines |
Mol File: | 123-78-4.mol |
D-ERYTHRO-SPHINGOSINE Chemical Properties |
Melting point | 81-82 °C |
Boiling point | 440.8°C (rough estimate) |
density | 0.9758 (rough estimate) |
refractive index | 1.5000 (estimate) |
storage temp. | −20°C |
solubility | chloroform: 20 mg/mL, clear, colorless to very faintly yellow |
form | Powder or Waxy Solid |
color | White to cream |
Merck | 14,8747 |
Stability: | Stable. Incompatible with strong acids, strong bases, strong oxidizing agents. |
CAS DataBase Reference | 123-78-4 |
MSDS Information |
Provider | Language |
---|---|
ACROS | English |
SigmaAldrich | English |
D-ERYTHRO-SPHINGOSINE Usage And Synthesis |
Chemical Properties | White Crystalline Solid |
Uses | Selective inhibitor of protein kinase C activity and phorbol dibutyrate binding in vitro in human platelets; does not inhibit protein kinase A or myosin light chain kinase; inhibits calmodulin-dependent enzymes; natural isomer of sphingosine |
Biological Activity | Inhibitor of protein kinase C and calmodulin-dependent enzymes, but may stimulate mast cells by activation of protein kinase C. |
Purification Methods | D-Sphingosine is purified by recrystallisation from EtOAc, Et2O or pet ether (60-80o). It is insoluble in H2O but is soluble in Me2CO, EtOH and MeOH. It has IR bands at 1590 and 875 cm-1, and is characterised as the tribenzoate m 122-123o (from 95% EtOH). [Tipton Biochemical Preparations 9 127 1962.] |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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