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Mecobalamin
Mecobalamin

Mecobalamin

Price USD1.00
Packge 1kg
  • Min. Order:1kg
  • Supply Ability:100KG
  • Time:2019-07-06

Product Details

  • Product Name Mecobalamin
  • CAS No. 13422-55-4
  • EINECS No.236-535-3
  • MFC63H90CoN13O14P
  • MW1343.4
  • AppearanceSolidDark Red
  • storage temp. Sealed in dry,Store in freezer, under -20°C
  • Melting point >190°C (dec.)
  • Water Solubility Partially soluble in cold water, hot water.

AD68

 
Mecobalamin Basic information
Pharmacological action Uses
Product Name: Mecobalamin
Synonyms: MECOBALAMIN;MECOBALAMINE;METHYLCOBALAMIN;cobalt-methylcobalamin;cobinamide,cobalt-methylderivative,hydroxide,dihydrogenphosphate(ester),;Methyl-5,6-dimethylbenzimidazolylcobalamin;Vitamin B12;Algobaz
CAS: 13422-55-4
MF: C63H91CoN13O14P
MW: 1344.38
EINECS: 236-535-3
Product Categories: PHARMACEUTICALS;Nutritional Supplements;Intermediates & Fine Chemicals;Vitamin B12;Nutrition Research;Vitamins;Vitamin Ingredients;API;Pharmaceutical intermediates
Mol File: 13422-55-4.mol
Mecobalamin Structure
 
Mecobalamin Chemical Properties
Melting point  >190°C (dec.)
storage temp.  −20°C
Water Solubility  Partially soluble in cold water, hot water.
InChIKey JEWJRMKHSMTXPP-WYVZQNDMSA-L
CAS DataBase Reference 13422-55-4
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36-26
WGK Germany  2
RTECS  GG3745000
HS Code  29362600
MSDS Information
Provider Language
SigmaAldrich English
 
Mecobalamin Usage And Synthesis
Pharmacological action Mecobalamin as vitamin B12 derivatives, should be called "methyl vitamin B12" according to the chemical structure of name, the functional groups of methylation can be involved in the biochemical process of methyl transfer activity, promoting to nucleic acid of nerve tissue, the metabolism of protein and fat, , can stimulate the synthesis of lecithin Schwann cells, repairing the damaged myelin, improving nerve conduction velocity; directly into nerve cells, and stimulating axon regeneration of damaged area; stimulating protein synthesis in nerve cells and enhanced synthetic metabolism of axons to prevent axonal degeneration; involved in nucleic acid synthesis, promoted hematopoietic function. The treatment is clinically used in diabetic neuropathy, long-term use of macrovascular complications of diabetes are the curative effect.
Mecobalamin is used for peripheral nerve disorders treatment drug, compared with other vitamin B12 preparations, having good transfer on the nervous tissue, through the methyl transfer reaction, can promote nucleic acid, protein lipid metabolism, repairing the damaged nerve tissue. In homocysteine synthetic egg ammonia acid process, it plays a role of coenzyme, especially by deoxyuridine synthesis of thymidine, promoting DNA and RNA synthesis of participation. Also in the experiment of glial cells, the drugs can improve methionine synthase activity and promote the synthesis of myelin lipids lecithin. Improving the nerve tissue metabolism, can promot axis cable and protein synthesis, make the delivery rate of the skeletal protein close to normal, maintain axonal functions. Besides mecobalamin injections can inhibit nerve tissue of abnormal impulse conduction, promoting redl blood cells mature, split, improving anemia. Mecobalamin can be quickly restored due to lack of B12 and reduce the number of rat erythrocytes, hemoglobin, hematocrit value. Used for megaloblastic red blood cell anemia and peripheral nerve disorder due to the lack of vitamin B12.
The above information is edited by the Chemicalbook Hanya.
Uses 1.It is used for the treatment of nervous system diseases, relieving pain and numbness, speeded relieving pain, improving pain caused by cervical spondylosis, treatment of sudden deafness, etc.
2.Methylcobalamin is a kind of endogenous coenzyme B12, participating in the one carbon unit cycle, playing an important role in the synthesis of methionine homocysteine methyl transfer reaction process.
Chemical Properties Dark Red Crystalline Powder
Uses One of the biologically active forms of vitamin B12; differing only by the substitution of a methyl for the cyano group. Coenzyme required in the biosynthesis of methionine. Vitamin (hematopoietic).
Uses ?Histamine receptor, Alzheimer research
Definition A vitamin B 12 analog used as an intermediate in the synthesis of methane. It is responsible for the methylation of inorganic mercury by anaerobic bacteria in bottom sediments. Through the action of methylcobalamin in an anaerobic bacteria in bottom sediments of aquatic systems, arsenic(III) is methylated to methanearsonic acid then to cacodylic acid.
 

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 

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career henan chemical co

Henan China
  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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