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Iron-dextran
Iron-dextran

Iron-dextran

Price USD1.00
Packge 1KG
  • Min. Order:1G
  • Supply Ability:100KG
  • Time:2019-07-06

Product Details

  • Product NameIron-dextran
  • CAS No. 9004-66-4
  • EINECS No.202-785-7
  • MFFeH2O4S
  • MW153.92348
  • AppearancesolutionVery Dark Red to Black
  • storage temp. Room Temperature
  • Water Solubility Iron, ~100?mg/mL in water

AD68

Iron-dextran Basic information
Product Name: Iron-dextran
Synonyms: a100;a100(pharmaceutical);b75;chinofer;dextranironcomplex;dextrofer75;eisendextran;fe-dextran
CAS: 9004-66-4
MF: FeH2O4S
MW: 153.92348
EINECS:  
Product Categories: API's;API
Mol File: 9004-66-4.mol
Iron-dextran Structure
 
Iron-dextran Chemical Properties
form  solution
EPA Substance Registry System Iron dextran(9004-66-4)
 
Safety Information
Hazard Codes  Xn,T
Risk Statements  40-42/43-43-45
Safety Statements  23-26-36/37/39-45-36-36/37-53
WGK Germany  -
RTECS  NI2200000
Hazardous Substances Data 9004-66-4(Hazardous Substances Data)
Toxicity LD50 i.v. in mice: 2240 mg Fe/kg (Beliles)
Iron-dextran Usage And Synthesis
Description Iron dextran is a dark brown, slightly viscous liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. Iron Dextran is used for the treatment of patients with documented iron deficiency in which oral administration is unsatisfactory or impossible. It is supplied as a parenteral preparation and is used as a hematinic. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1292)
Iron-Dextran is for the parenteral treatment of iron-deficiency anemia in humans and baby pigs. Can be used as a reagent.
Chemical Properties Light to dark brown powder. Colloidal suspension of an iron-dextran complex in water. pH 5.2-6.5.
History The therapeutic value of colloidal iron preparations was first reported in the 1950's by London and Twigg. Numerous attempts have been made to improve these iron preparations Thus dextran ([h] 0.05) is first heated with alkali, and is then neutralized in the presence of ferric chloride solution. Studies on this product have revealed that each particle consists of a central iron core, approximately 3nm diameter, surrounded by a dextran sheath of approximately 13nm diameter. The complex is visualized as a particle formed by a protective sheath of dextran attached by terminal metasaccharinic acid units to a b-FeOOH core. A solution of this complex containing 5% iron and 20% dextran (Imferon ™ ) is suitable for intramuscular and intravenous injection for treating iron deficiency anemia. The product is currently used widely for treating anemia in new-born piglets.
The use of these preparations has been re-examined in humans and a dramatic rise in hemoglobin was reported following intravenous infusion. The solution is best administered together with glucose solutions.
Reactivity Profile Iron-dextran is unstable at a pH of 5 and decomposes at 149-158° F. Iron-dextran may be sensitive to prolonged exposure to air.
Health Hazard SYMPTOMS: The symptoms associated with exposure to Iron-dextran are headaches, vomiting, and dizziness.
Fire Hazard Iron-dextran is combustible.

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 

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career henan chemical co

Henan China
  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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