Daunorubicin hydrochloride
| Price | USD1.00 |
| Packge | 1KG |
- Min. Order:1G
- Supply Ability:100KG
- Time:2019-07-06
Product Details
- Product NameDaunorubicin hydrochloride
- CAS No.23541-50-6
- EINECS No.245-723-4
- MFC27H29NO10.ClH
- MW563.98
- Appearancesolidred to deep red
- Melting point 190°C (dec)
- storage temp. Inert atmosphere,2-8°C
- Water Solubility Soluble in water (50 mM)
AD68
| Daunorubicin hydrochloride Basic information |
| Product Name: | Daunorubicin hydrochloride |
| Synonyms: | 5,12-Naphthacenedione,8-acetyl-10-[(3-aMino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-Methoxy-,hydrochloride (1:1), (8S,10S)-;5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride (1:1), (8S,10S)-;Daunorubicin hydrochloride, >=98%;Daunorubicin HCI;Daunorubicin Hydrochloride 98.9%;WP900 HYDROCHLORIDE;daunoblastin;daunoblastina |
| CAS: | 23541-50-6 |
| MF: | C27H30ClNO10 |
| MW: | 563.98 |
| EINECS: | 245-723-4 |
| Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Antitumour;Carbohydrates & Derivatives;Chiral Reagents;Heterocycles;API;Anti-cancer&immunity |
| Mol File: | 23541-50-6.mol |
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| Daunorubicin hydrochloride Chemical Properties |
| Melting point | 190°C (dec) |
| alpha | D20 +248 ±5° (c = 0.05-0.1 in methanol) |
| storage temp. | −20°C |
| form | solid |
| color | red to deep red |
| λmax | 477nm(H2O)(lit.) |
| Sensitive | Hygroscopic |
| Merck | 14,2832 |
| Stability: | Stability |
| EPA Substance Registry System | 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3, 6-trideoxy-.alpha.-L-lyxo- hexopyranosyl)oxy]-7,8,9, 10-tetrahydro-6,8,11-trihydroxy- 1-methoxy-, hydrochloride, (8S,10S)-(23541-50-6) |
| Safety Information |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-40-42/43-36/37/38-20/21/22 |
| Safety Statements | 22-36/37-45-37/39-36-26 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | HB7878000 |
| F | 3-10 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Toxicity | LD50 in mice (mg/kg): 26 i.v. (DiMarco, 1969) |
| Daunorubicin hydrochloride Usage And Synthesis |
| Chemical Properties | Dark Red Crystals |
| Uses | Antineoplastic;DNA intercaling |
| Uses | anti-neoplastic LD50 in mice 26 mg/kg |
| Uses | A DNA intercalator which may suppress acute leukemia proliferation |
| Uses | Anthracycline antibiotic related to the rhodomycins. Antineoplastic |
| General Description | Orange-red powder. Thin red needles decomposing at 188-190°C. An anti-cancer drug. |
| Air & Water Reactions | Water soluble. |
| Reactivity Profile | Daunorubicin hydrochloride may emit toxic oxides of nitrogen when heated. |
| Biological Activity | Anticancer agent that is clinically used to treat nonlymphocytic leukaemia. Inhibits RNA and DNA synthesis and causes DNA fragmentation in vivo . |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
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- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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