S-(-)-Carbidopa
| Price | USD1.00 |
| Packge | 1KG |
- Min. Order:1G
- Supply Ability:100KG
- Time:2019-07-06
Product Details
- Product Name S-(-)-Carbidopa
- CAS No.28860-95-9
- EINECS No.657-445-4
- MFC10H14N2O4
- MW226.23
- AppearancepowderWhite to Off-White
- storage temp. -20°C
- Melting point 203-205° (dec); mp 208°
- Boiling point 367.84°C (rough estimate)
- density 1.2616 (rough estimate)
AD68
| S-(-)-Carbidopa Basic information |
| Product Name: | S-(-)-Carbidopa |
| Synonyms: | 4-dihydroxy-alpha-methyl-alpha-hydrazino-(s)-benzenepropanoicaci;4-dihydroxy-alpha-methyl-alpha-hydrazino-l-hydrocinnamicaci;alpha-methyldopahydrazine;-Hydrazino-3,4-dihydroxy-methylbenzenep-ropanicacid;-Hydrazino-3,4-dihydroxy-methylhy-drocinnamicacid;hydrazino-alpha-methyldopa;l-alpha-methyldopahydrazine;mk486 |
| CAS: | 28860-95-9 |
| MF: | C10H14N2O4 |
| MW: | 226.23 |
| EINECS: | 249-271-9 |
| Product Categories: | L-Aromatic Amino Acid Decarboxylase;API;Lodosyn |
| Mol File: | 28860-95-9.mol |
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| S-(-)-Carbidopa Chemical Properties |
| Melting point | 203-205° (dec); mp 208° |
| alpha | D -17.3° (methanol) |
| Boiling point | 367.84°C (rough estimate) |
| density | 1.2616 (rough estimate) |
| refractive index | 1.5000 (estimate) |
| storage temp. | −20°C |
| form | powder |
| CAS DataBase Reference | 28860-95-9(CAS DataBase Reference) |
| Safety Information |
| WGK Germany | 3 |
| RTECS | MW5298000 |
| S-(-)-Carbidopa Usage And Synthesis |
| Chemical Properties | White Solid |
| Uses | (S)-(-)-Carbidopa is a peripheral decarboxylase inhibitor that is commonly used in combination with L-DOPA (D533751) for treatment of Parkinsonism. S(-)-Carbidopa ( has also been shown to prolong the elimination half-life of L-DOPA from blood plasma and skeletal muscle. |
| Uses | in combinaison with levodopa as antiparkinsonian;inhibits aromatic-L-amino-acid decarboxylase (DOPA Decarboxylase or DDC) |
| Definition | ChEBI: 3-(3,4-Dihydroxyphenyl)propanoic acid in which the hydrogens alpha- to the carboxyl group are substituted by hydrazinyl and methyl groups (S-configuration). Carbidopa is a dopa decarboxylase inhibitor, so prevents conversi n of levodopa to dopamine. It has no antiparkinson activity by itself, but is used (commonly as its hydrate) in the management of Parkinson's disease to reduce peripheral adverse effects of levodopa. |
| Biological Activity | Peripheral decarboxylase inhibitor, used in combination with levodopa for treatment of Parkinsonism. |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
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- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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