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Sinomenine
Sinomenine

Sinomenine

Price USD1.00
Packge 1KG
  • Min. Order:1G
  • Supply Ability:100KG
  • Time:2019-07-06

Product Details

  • Product NameSinomenine
  • CAS No.115-53-7
  • EINECS No.204-094-6
  • MFC19H23NO4
  • MW329.39
  • AppearanceneatWhite to off-white
  • Melting point 180 °C (dec.)(lit.)
  • storage temp. Store at +4°C
  • Boiling point 466.98°C (rough estimate)
  • density 1.2012 (rough estimate)

AD68

Sinomenine Basic information
Product Name: Sinomenine
Synonyms: 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-9-alpha,13-alpha,14-alpha-mo;9-alpha,13-alpha,14-alpha-morphinan-6-one,7,8-didehydro-4-hydroxy-3,7-dimethox;rphinan-6-one;y-17-methyl-;SABIANINE A;SINOMENIN;SINOMENINE;(9alpha,13alpha,14alpha)-7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one
CAS: 115-53-7
MF: C19H23NO4
MW: 329.39
EINECS: 204-094-6
Product Categories: Alkaloids;Natural Plant Extract;Asymmetric Synthesis;Chiral Building Blocks;Complex Molecules;API;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors
Mol File: 115-53-7.mol
Sinomenine Structure
 
Sinomenine Chemical Properties
Melting point  180 °C (dec.)(lit.)
alpha  D26 -71° (c = 2.1 in alc)
Boiling point  466.98°C (rough estimate)
density  1.2012 (rough estimate)
refractive index  1.5000 (estimate)
storage temp.  Store at +4°C
Merck  13,8620
 
Safety Information
Hazard Codes  T,Xn
Risk Statements  45-46-23/24/25-36/37/38-20/21/22-48/20/22-40-22-63
Safety Statements  53-22-26-36/37/39-45-36/37-24/25
RIDADR  1544
WGK Germany  3
RTECS  QD2170000
9
HazardClass  6.1(b)
PackingGroup  III
Toxicity LD50 orally in mice: 580 mg/kg (Fu)
Sinomenine Usage And Synthesis
Uses weak abortifacient, immunosuppressant, analgesic, antiinflammatory; LD50 (po) 580 mg/kg; (ip) 285 mg/kg(mouse)
Biological Activity Natural anti-inflammatory morphinan analog. Causes degranulation of mast cells in mammalian tissues to release histamine and suppresses production of proinflammatory cytokines. Also displays antinociceptive activity, possibly through activation of the μ -opioid receptor. Stimulates short-term renewal of human embryonic stem cells (ESCs) in vitro .

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 
  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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