Fluoxetine
| Price | USD1.00 |
| Packge | 1KG |
- Min. Order:1G
- Supply Ability:100KG
- Time:2019-07-06
Product Details
- Product NameFluoxetine
- CAS No.54910-89-3
- EINECS No.611-209-7
- MFC17H18F3NO
- MW309.33
- AppearanceLiquidColorless to light yellow
- Melting point 158 °C
- Boiling point 395.1±42.0 °C(Predicted)
- density 1.159±0.06 g/cm3(Predicted)
- storage temp. 2-8°C(protect from light)
AD68
| Fluoxetine Basic information |
| Product Name: | Fluoxetine |
| Synonyms: | (+/-)-n-methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine;METHYL-[3-PHENYL-3-(4-TRIFLUOROMETHYLPHENOXY)PROPYL]AMINE;AURORA KA-7692;FLUOXETINE;(+-)-benzenepropanamin;(+)or(-)-n-methyl-3-phenyl-3-(alpha,alpha,alpha-trifluoro-p-tolyl)oxy)prop;(+)or(-)-n-methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine;dl-3-(p-trifluoromethylphenoxy)-n-methyl-3-phenylpropylamine |
| CAS: | 54910-89-3 |
| MF: | C17H18F3NO |
| MW: | 309.33 |
| EINECS: | 244-296-1 |
| Product Categories: | API;CEFTIN |
| Mol File: | 54910-89-3.mol |
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| Fluoxetine Chemical Properties |
| CAS DataBase Reference | 54910-89-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Fluoxetine(54910-89-3) |
| Safety Information |
| MSDS Information |
| Provider | Language |
|---|---|
| (+/-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine | English |
| Fluoxetine Usage And Synthesis |
| Chemical propertis | Fluoxetine Hydrochloride: White or white crystalline solids with a melting point of 158.4 to 158.9℃. Soluble in methanol or ethanol, dissolved in acetonitrile, acetone, or chloroform, and slightly soluble in ethyl acetate, dichloromethane, or water(with sonication at pHl.2，4.5，7.0).Almost insoluble in cyclohexane, hexane or toluene. Solubility(mg/m1)：Methanol and ethanol > 100, Acetone, acetonitrile and chloroform 33~100, dichloromethane 5~10, water 1~2, ethyl acetate 2 ~ 2.5, Cyclohexane, hexane and toluene 0.5 ~ 0.67. The maximum solubility in water: 14mg/ml. UV maximum absorption (methanol):227，264，268，275nm (E1cm1%372.0，29.2，29.3，21.5). Acute toxic of LD50 for large rate and small rat (mg/kg): 248, 452 oral administrations.  |
| Antidepressant | Fluoxetine is an antidepressant of the selective serum reabsorption inhibitor (SSRI) type.The drug takes the form of Fluoxetine hydrochloride. Its trade name is "Prozac". The drug was developed by the Eli Lilly and Company. It has been launched into market for sale since the 1990s. This drug is used for the treatment of adult depression, obsessive-compulsive disorder, bulimia nervosa and the panic disorder that has or does not have the phobia of the square. It has good antidepressant effect and is widely used in clinical practice as a first-line antidepressant.The main pharmacological effect is to selectively inhibit the reuptake of 5 hydroxytryptamine (HT), which is released before the synapse of the central nervous system.It is also known as a selective 5- serotonin reuptake inhibitor. For other receptors, such as alpha adrenergic, beta adrenergic, 5- serotonin, and dopamine, fluoxetine had almost no binding force. Fluoxetine is well absorbed from the gastrointestinal tract after oral administration.The plasma concentration is about 6~8 hours, and eating does not affect its bioavailability. About 95% are combined with plasma proteins and are widely distributed.After taking the medicine for several weeks, the steady plasma concentration will be reached.By metabolism of the liver, the active metabolite, norfluoxetine is generated by demethylation. The half-life of fluoxetine is 4-6 days, and norfluoxetine is 4-16 days.It was mainly excreted by kidney. Because it can be secreted to breast milk, it is suggested to be cautious to pregnant women and breast-feeding women. |
| Precautions |
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| Uses | antibacterial |
| Uses | Rivastigmine Metabolite |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
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- 2024-01-23
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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