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Dexrazoxane
Dexrazoxane

Dexrazoxane

Price USD1.00
Packge 1KG
  • Min. Order:1G
  • Supply Ability:100KG
  • Time:2019-07-06

Product Details

  • Product NameDexrazoxane
  • CAS No.24584-09-6
  • EINECS No.206-169-7
  • MFC11H16N4O4
  • MW268.27
  • Appearancepowderwhite to off-white
  • Melting point 194-196°C
  • storage temp. 2-8°C
  • Boiling point 531.5±50.0 °C(Predicted)
  • density 1.333±0.06 g/cm3(Predicted)

AD68

Dexrazoxane Basic information
Product Name: Dexrazoxane
Synonyms: DEXRAZOXANE;(s)-4,4'-(1-methyl-1,2-ethanediyl)bis-2,6-piperazinedione;4’-(1-methyl-1,2-ethanediyl)bis-6-piperazinedion(+)-4;4’-propylenedi-6-piperazinedion(+)-4;adr529;cardioxane;DEXTRAZOXANE;DEXTRORAZOXANE
CAS: 24584-09-6
MF: C11H16N4O4
MW: 268.27
EINECS:  
Product Categories: Chelating Agent;API
Mol File: 24584-09-6.mol
Dexrazoxane Structure
 
Dexrazoxane Chemical Properties
Melting point  194-196°C
alpha  D +11.35° (c = 5 in DMF)
storage temp.  Desiccate at RT
solubility  DMSO: >20mg/mL
pka 2.1(at 25℃)
color  white to off-white
Merck  14,8123
CAS DataBase Reference 24584-09-6(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
RIDADR  UN 2811 6.1 / PGIII
RTECS  TL6390000
Hazardous Substances Data 24584-09-6(Hazardous Substances Data)
MSDS Information
 
 
Dexrazoxane Usage And Synthesis
Biological Activity Topoisomerase II inhibitor and intracellular ion chelator. Bridges and stabilizes an interface between two ATPase promoters to inhibit topoisomerase II activity. Cardioprotective when co-administered with doxorubicin; decreases formation of reactive oxygen species (ROS) and activates the PI3K/Akt survival pathway.
 

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 

Recommended supplier

  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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