PBP
| Price | USD1.00 |
| Packge | 1KG |
- Min. Order:1G
- Supply Ability:100KG
- Time:2019-07-06
Product Details
- Product Name PBP
- CAS No.103-16-2
- EINECS No.203-083-3
- MFC13H12O2
- MW200.23
- InChIKeyVYQNWZOUAUKGHI-UHFFFAOYSA-N
- AppearancePowder, Crystals, and/or ChunksOff-white to beige to brown
- Melting point 119-120 °C (lit.)
- Water Solubility slightly soluble
- density 1,26 g/cm3
- storage temp. Store below +30°C.
- Boiling point 297.96°C (rough estimate)
AD68
| PBP Basic information |
| Product Name: | PBP |
| Synonyms: | MONOBENZONE;PBP;P-BENZYLOXYPHENOL;P-HYDROXYPHENYL BENZYL ETHER;HYDROQUINONE MONOBENZYL ETHER;Benzyl hydroquinone;BENZYL P-HYDROXYPHENYL ETHER;4-BENZYLOXYPHENOL |
| CAS: | 103-16-2 |
| MF: | C13H12O2 |
| MW: | 200.23318 |
| EINECS: | 203-083-3 |
| Product Categories: | API intermediates;Bifunctional Compounds (Building Blocks for Liquid Crystals);Building Blocks for Liquid Crystals;Functional Materials;treat Vitiligo;whiten agent;cosmetics;B;Bioactive Small Molecules;Building Blocks;C9 to C20+;Cell Biology;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Phenols;API;SANODIN |
| Mol File: | 103-16-2.mol |
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| PBP Chemical Properties |
| Melting point | 119-120 °C(lit.) |
| Boiling point | 297.96°C (rough estimate) |
| density | 1,26 g/cm3 |
| refractive index | 1.5906 (estimate) |
| storage temp. | -20°C |
| form | Powder, Crystals, and/or Chunks |
| color | Off-white to beige to brown |
| Water Solubility | slightly soluble |
| Merck | 14,6248 |
| BRN | 1958305 |
| InChIKey | VYQNWZOUAUKGHI-UHFFFAOYSA-N |
| CAS DataBase Reference | 103-16-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Monobenzone(103-16-2) |
| EPA Substance Registry System | Phenol, 4-(phenylmethoxy)-(103-16-2) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36-43 |
| Safety Statements | 24/25-26-37 |
| WGK Germany | 2 |
| RTECS | SJ7700000 |
| Hazard Note | Irritant |
| TSCA | Yes |
| HS Code | 29095090 |
| Hazardous Substances Data | 103-16-2(Hazardous Substances Data) |
| Toxicity | LD50 i.p. in mice: >600 mg/kg (Takahashi) |
| PBP Usage And Synthesis |
| Abstract | Monobenzone, also called 4-(Benzyloxy)phenol and monobenzyl ether of hydroquinone (MBEH) is an organic chemical in the phenol family with chemical formula C6H5CH2OC6H4OH. It is used as a topical drug for medical depigmentation. Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water. The topical application of monobenzone in animals, increases the excretion of melanin from the melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. |
| Treatment for vitiligo | Monobenzone may cause destruction of melanocytes and permanent depigmentation.Hyperpigmented skin appears to fade more rapidly than does normal skin, and exposure to sunlight reduces the depigmenting effect of the drug. The histology of the skin after depigmentation with topical monobenzone is the same as that seen in vitiligo; the epidermis is normal except for the absence of identifiable melanocytes.This function enables it treat the uneven appearance of the skin due to a loss of skin color (vitiligo). It works by permanently removing color from normal skin located around skin with vitiligo. This will help to make the appearance of the skin more even. What calls for special attention is that: Do not use this drug to treat other skin discoloration problems ("sun spots," "age spots," freckles, skin discoloration caused by hormone medicine, perfumes, pregnancy, or skin trauma). Monobenzone is not a mild cosmetic bleach. Because it causes a permanent discoloration of the skin, it may not be the right treatment for these other skin conditions. Besides, Monobenzone is also being considered for the treatment of Melanoma. |
| How to use | This medication is for use on the skin only. Apply a thin layer of the medication to normal-colored skin, usually 2-3 times daily or as directed by your doctor. Avoid getting this product in your eyes or on the inside of your nose or mouth. If you do get this medication in those areas, flush with plenty of water.After using this medication, the skin will be permanently affected and sensitive to sunlight. Avoid prolonged exposure to sunlight, tanning booths, and sunlamps. Always use a sunscreen of SPF 15 or greater, and wear protective clothing when outdoors.It may take up to 4 months before the full benefit of this drug takes effect. Once the desired skin color is achieved, this medication is applied only as needed to maintain your new skin color (usually 2 times a week).Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day.Inform your doctor if your condition persists or worsens after 4 months. You should not use this medication if you are allergic to monobenzone. Do not use monobenzone on any areas that are not affected by vitiligo. |
| Category | Toxic substance |
| Toxic grading | Moderate toxicity |
| Acute toxicity | Abdomen-rat LD50: 4500 mg/kg |
| Stimulate data | Skin-guinea pigs 5%/48 hours, mild grade. |
| Flammability hazard characteristics | The drug is combustible, and combustion releases stimulus smoke. |
| Storage | Ventilated warehouse, low temperature, dry; Separated from food raw materials. |
| Extinguishing agent | Dry powder, foam, sand, carbon dioxide, mist water. |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
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- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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