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Guaifenesin
Guaifenesin

Guaifenesin

Price USD1.00
Packge 1KG
  • Min. Order:1G
  • Supply Ability:100KG
  • Time:2019-07-06

Product Details

  • Product NameGuaifenesin
  • CAS No.93-14-1
  • EINECS No.202-222-5
  • MFC10H14O4
  • MW198.22
  • InChIKeyHSRJKNPTNIJEKV-UHFFFAOYSA-N
  • AppearanceneatWhite to Off-White
  • Water Solubility 5 g/100 mL (25 ºC)
  • Boiling point 215 °C (19 mmHg)
  • Melting point 77-81 °C
  • storage temp. 2-8°C
  • density 1.1825 (rough estimate)

AD68

Guaifenesin Basic information
Description References
Product Name: Guaifenesin
Synonyms: 1,2-Dihydroxy-3-(2-methoxyphenoxy)propane;1,2-Propanediol, 3-(2-methoxyphenoxy)-;1,2-Propanediol, 3-(o-methoxyphenoxy)-;2/G;2-G;3-(2-Methoxyphenosy)-1,2-propamediol;3-(2-methoxyphenoxy)-2-propanediol;3-(o-methoxyphenoxy)-2-propanediol
CAS: 93-14-1
MF: C10H14O4
MW: 198.22
EINECS: 202-222-5
Product Categories: Benzhydrols, Benzyl & Special Alcohols;Aromatics Compounds;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Methocarbamol;Building Blocks;C10;Chemical Synthesis;Ethers;Organic Building Blocks;Oxygen Compounds;API;MUCINEX
Mol File: 93-14-1.mol
Guaifenesin Structure
 
Guaifenesin Chemical Properties
Melting point  77-81 °C
Boiling point  215 °C (19 mmHg)
density  1.1825 (rough estimate)
refractive index  1.5550 (estimate)
Fp  215°C/19mm
storage temp.  Refrigerator
solubility  50g/l (experimental)
Water Solubility  5 g/100 mL (25 ºC)
Merck  14,4555
BRN  2049375
InChIKey HSRJKNPTNIJEKV-UHFFFAOYSA-N
CAS DataBase Reference 93-14-1(CAS DataBase Reference)
NIST Chemistry Reference 3-(O-methoxyphenoxy)-1,2-propanediol(93-14-1)
EPA Substance Registry System 1,2-Propanediol, 3-(2-methoxyphenoxy)-(93-14-1)
 
Safety Information
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26-36
WGK Germany  1
RTECS  TY8400000
Hazard Note  Harmful
TSCA  Yes
Hazardous Substances Data 93-14-1(Hazardous Substances Data)
Guaifenesin Usage And Synthesis
Description Guaifenesin is an oral expectorant drug. The expectorant action of guaifenesin is mediated by stimulation of the gastrointestinal tract. It is a common ingredient in prescription and over-the-counter medications used to treat cough due to colds and minor upper respiratory infections.
References [1] Peter V. Dicpinigaitis and Yvonne E. Gayle, Effect of Guaifenesin on Cough Reflex Sensitivity, 2003, vol. 124, 2178-2181
[2] Leonid Kagan, Eran Lavy and Ammon Hoffmann, Effect of mode of administration on guaifenesin pharmacokinetics and expectorant action in the rat model, Pulmonary Pharmacology & Therapeutics, 2009, vol. 22, 260-265
Chemical Properties White Solid
Uses Centrally acting muscle relaxant with expectorant properties
Uses Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
 

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 
  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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