Aceclofenac
| Price | USD1.00 |
| Packge | 1KG |
- Min. Order:1G
- Supply Ability:100KG
- Time:2019-07-06
Product Details
- Product NameAceclofenac
- CAS No.89796-99-6
- EINECS No.641-844-5
- MFC16H13Cl2NO4
- MW354.18
- Appearancepowderoff-white to light tan
- Melting point 149-153°C
- storage temp. 2-8°C
- Boiling point 486.0±45.0 °C(Predicted)
- density 1.455±0.06 g/cm3(Predicted)
- Water Solubility 32mg/L(32 ºC)
AD68
| Aceclofenac Basic information |
| Product Name: | Aceclofenac |
| Synonyms: | ACECLOFENAC;ACECLOFENAC-D2;Airtal;Falcol;Gerbin;Glycolic Acid [o-(2,6-Dichloroanilino)phenyl]acetate Ester;PR-82/3;Preservex |
| CAS: | 89796-99-6 |
| MF: | C16H13Cl2NO4 |
| MW: | 354.18 |
| EINECS: | 205-783-4 |
| Product Categories: | Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;Lipid signaling;Aromatics;Free Base API;API;AIRTAL |
| Mol File: | 89796-99-6.mol |
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| Aceclofenac Chemical Properties |
| Melting point | 149-153°C |
| RTECS | CY1577900 |
| storage temp. | -20°C Freezer |
| solubility | Soluble in DMSO |
| color | off-white to light tan |
| Merck | 14,22 |
| InChIKey | MNIPYSSQXLZQLJ-UHFFFAOYSA-N |
| CAS DataBase Reference | 89796-99-6(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | T,N |
| Risk Statements | 25-36-50/53 |
| Safety Statements | 26-45-60-61 |
| RIDADR | UN 2811 6.1 / PGIII |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29224999 |
| Aceclofenac Usage And Synthesis |
| Description | Aceclofenac is a kind of orally administrated phenylacetic acid derivative with analgesic and anti-inflammatory properties. It can alleviate various kinds of painful conditions. It can reduce the pain, disease severity and improve the functional capacity of the knee. For patients with rheumatoid arthritis, it can reduce the joint inflammation, pain intensity and the duration of morning stiffness. It exerts effects on a variety of mediators of inflammation. It can block the synthesis of the inflammatory cytokines interleukin (IL)-1β and tumor necrosis factor, and inhibits prostaglandin E2 (PGE) production. Aceclofenac is well tolerated with most adverse events being minor and reversible. |
| Chemical Properties | White Crystalline Solid |
| Uses | Aceclofenac is an anti-inflammatory and analgesic drug. |
| Uses | Relief of pain and inflammation |
| Uses | Labeled Aceclofenac, intended for use as an internal standard for the quantification of Aceclofenac by GC- or LC-mass spectrometry. |
| Uses | Anti-inflammatory; analgesic |
| Definition | ChEBI: A monocarboxylic acid that is the carboxymethyl ester of diclofenac. A non-steroidal anti-inflammatory drug related to diclofenac, it is used in the management of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. |
| References | Brogden, Rex N., and Lynda R. Wiseman. "Aceclofenac. A review of its pharmacodynamic properties and therapeutic potential in the treatment of rheumatic disorders and in pain management." Drugs 52.1 (1996): 113-124. Raza, Kaisar, et al. "Topical delivery of aceclofenac: challenges and promises of novel drug delivery systems." BioMed research international 2014 (2014). Dooley, Mukta, Caroline M. Spencer, and Christopher J. Dunn. "Aceclofenac: a reappraisal of its use in the management of pain and rheumatic disease." Drugs 61.9 (2000): 1351-1378. |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
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- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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