Rosiglitazone maleate
| Price | USD1.00 |
| Packge | 1KG |
- Min. Order:1G
- Supply Ability:100KG
- Time:2019-07-06
Product Details
- Product NameRosiglitazone maleate
- CAS No. 155141-29-0
- EINECS No.642-163-6
- MFC22H23N3O7S
- MW473.5
- AppearanceWhite powderWhite
- Melting point 235-240°C
- storage temp. 2-8°C
AD68
| Rosiglitazone maleate Basic information |
| Product Name: | Rosiglitazone maleate |
| Synonyms: | 5-((4-[2-(METHYL-2-PYRIDINYLAMINO)-ETHOXY]-PHENYL)-METHYLENE)-2,4-THIAZOLIDINEDIONE;5-{p-[2-(methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedione maleate;ROSIGLITAZONE MALEATE;RosiglitazoneTartrate;Avandi;BRL-49653c;RSIGLITAZONEMALEATE;5-(4-(2-(Methyl(pyridin-2-yl)aMino)ethoxy)benzyl)thiazolidine-2,4-dione Maleate |
| CAS: | 155141-29-0 |
| MF: | C22H23N3O7S |
| MW: | 473.5 |
| EINECS: | 1312995-182-4 |
| Product Categories: | Active Pharmaceutical Ingredients;Antidiabetic;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Rosiglitazone;Heterocycles;Sulfur & Selenium Compounds;Inhibitor;API |
| Mol File: | 155141-29-0.mol |
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| Rosiglitazone maleate Chemical Properties |
| Melting point | 235-240°C |
| storage temp. | -20°C Freezer |
| pka | 6.1; 6.8(at 25℃) |
| CAS DataBase Reference | 155141-29-0(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 20/21/22-36/38 |
| Safety Statements | 24/25-37/39-26 |
| Rosiglitazone maleate Usage And Synthesis |
| Chemical Properties | White To Off-White Solid |
| Uses | Insulin sensitizer; binds to peroxisome proliferator activated receptor gamma (PPAR- γ). |
| Uses | Thiazole alkanes antidiabetic drug |
| Uses | Thiazolidinediones (TZDs) are a group of structurally related peroxisome proliferator-activated receptor γ (PPARγ) agonists with antidiabetic actions in vivo. Rosiglitazone is a prototypical TZD that has served as a reference compound for this class. It is a potent and selective PPARγ ligand that binds to the PPARγ ligand-binding domain with a Kd value of 43 nM. It activates luciferase-based expression constructs PPARγ1 and PPARγ2 with EC50 values of approximately 30 nM and 100 nM, respectively. Rosiglitazone is active in vivo as an antidiabetic agent in the ob/ob mouse model, and has been used as an oral hypoglycemic agent in the treatment of type 2 diabetes in humans for many years.[Cayman Chemical] |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
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- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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