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Carvedilol
Carvedilol

Carvedilol

Price USD1.00
Packge 1KG
  • Min. Order:1G
  • Supply Ability:100KG
  • Time:2019-07-06

Product Details

  • Product NameCarvedilol
  • CAS No.72956-09-3
  • EINECS No.1308068-626-2
  • MFC24H26N2O4
  • MW406.47
  • Appearancesolidwhite to off-white
  • Melting point 113-117°C
  • storage temp. 2-8°C
  • Boiling point 655.2±55.0 °C(Predicted)
  • density 1.250±0.06 g/cm3(Predicted)
  • Water Solubility 449.2ug/L(22.5 ºC)

AD68

Carvedilol Basic information
Product Name: Carvedilol
Synonyms: 1-(9h-carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)-2-propano;CARVEDILOL;COREG;DIMITONE;DQ-2466;DILATREND;BM-14190;1-(9H-CARBAZOL-4-YLOXY)-3-[[2-(2-METHOXYPHENOXY)ETHYL]AMINO]-2-PROPANOL
CAS: 72956-09-3
MF: C24H26N2O4
MW: 406.47
EINECS: 1308068-626-2
Product Categories: Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Adrenoceptor;Aromatics;Heterocycles;API;LEVAQUIN;Cardiovascular Drugs
Mol File: 72956-09-3.mol
Carvedilol Structure
 
Carvedilol Chemical Properties
Melting point  113-117°C
storage temp.  Store at +4°C
solubility  DMSO: >20mg/mL
color  white to off-white
Merck  14,1873
CAS DataBase Reference 72956-09-3(CAS DataBase Reference)
 
Safety Information
Hazard Codes  N,Xn
Risk Statements  51/53-36/37/38-20/21/22
Safety Statements  61-36-26
RIDADR  UN 3077 9/PG 3
RTECS  UA8670000
HazardClass  IRRITANT
PackingGroup  III
Hazardous Substances Data 72956-09-3(Hazardous Substances Data)
Carvedilol Usage And Synthesis
Chemical Properties Colourless Crystalline Solid
Uses A nonselective -adrenergic blocker with a1-blocking activity. An antihypertensive used in the treatment of congestive heart failure.
Uses An α1- and β-adrenergic receptor antagonist.
Uses antibacterial
Uses Carvedilol is a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure.
Uses veterinary use
Uses For the treatment of mild or moderate (NYHA class II or III) heart failure of ischemic or cardiomyopathic origin.
Definition ChEBI: A member of the class of carbazoles that is an adrenergic antagonist with non-selective beta- and alpha-1 receptor blocking properties which helps in the management of congestive heart failure.
Biological Activity Potent β -adrenoceptor and α 1 -adrenoceptor antagonist (K i values are 0.81, 0.96 and 2.2 nM for β 1 -, β 2 - and α 1 -adrenoceptors respectively) that displays antihypertensive and peripheral vasodilatory activity. Blocks cardiac inward-rectifier K + (K IR ) channels, voltage-dependent Ca 2+ channels and exhibits antioxidant properties at higher concentrations.
 
 

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 

Recommended supplier

career henan chemical co

Henan China
  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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