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Testosterone
Testosterone

Testosterone

Price USD1.00
Packge 1KG
  • Min. Order:1G
  • Supply Ability:100KG
  • Time:2019-07-06

Product Details

  • Product NameTestosterone
  • CAS No.58-22-0
  • EINECS No.200-370-5
  • MFC19H28O2
  • MW288.43
  • InChIKeyMUMGGOZAMZWBJJ-KRHBYBJCNA-N
  • Appearancepowder
  • storage temp. 2-8°C
  • Melting point 152-156 °C
  • Boiling point 370.65°C (rough estimate)
  • density 1.0484 (rough estimate)
  • Water Solubility 22.79mg/L(20 ºC)

AD68

Testosterone Basic information
Chemical Properties Indications and Uses Pharmacokinetics Application in Particular Diseases
Product Name: Testosterone
Synonyms: testred;TESTOSTERONE;testex;testoderm;TESTOSTERON;ORQUISTERON;oreton;PRIMOTESTON
CAS: 58-22-0
MF: C19H28O2
MW: 288.42
EINECS: 200-370-5
Product Categories: MI;TPI;Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Intracellular receptor;Steroid and Hormone;API;testosterone;TESTIM;Inhibitors;4-CPRC ada@tuskwei.com whatsapp;8618031153937
Mol File: 58-22-0.mol
Testosterone Structure
 
Testosterone Chemical Properties
Melting point  152-156 °C
alpha  101 º (c=1, dioxane 25 ºC)
Boiling point  370.65°C (rough estimate)
density  1.0484 (rough estimate)
refractive index  1.4709 (estimate)
Fp  5 °C
storage temp.  2-8°C
solubility  45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble18.2 mg/ml
Merck  13,9255
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference 58-22-0(CAS DataBase Reference)
NIST Chemistry Reference Testosterone(58-22-0)
EPA Substance Registry System Androst-4-en-3-one, 17-hydroxy-, (17.beta.)-(58-22-0)
 
Safety Information
Hazard Codes  T,Xn,F
Risk Statements  60-61-11-19-20-40-63-45-36-20/21/22-38
Safety Statements  53-45-24/25-36/37-26-16
RIDADR  UN 2252 3/PG 2
WGK Germany  3
RTECS  XA3030000
Hazardous Substances Data 58-22-0(Hazardous Substances Data)
Testosterone Usage And Synthesis
Chemical Properties White crystalline powder with no aroma. Its melting point is 155℃, specific rotary power is [α]24D+109° (4%, ethanol), and its ethanol solution has the greatest absorbance at a wavelength of 240nm. It is easily soluble in ethanol (1:5), soluble in ether (1:100), and insoluble in water. LD50 (Large mice, venal transfusion) 326mg/kg. Studies show that it has latent carcinogenic effects on test animals.
Indications and Uses Testosterone is the main natural male sex hormone in mammals and is a steroid hormone with 19 carbon atoms. It is the main male sex hormone secreted by the testes, and it is also the most active male sex hormone. It promotes humans’ and animals’ sex organ and secondary sex characteristic development, sperm maturation, and protein metabolism for muscle strengthening. Testosterone controls the growth and development of male sex organs and male secondary sex characteristics. It is mainly used in replacement therapy for eunuchism, treatment for male menopause syndrome, and treatment for impotence, and it is also used in biochemical research.
Pharmacokinetics Testosterone can bind non-specifically with plasma albumins in blood, and it can also bind with plasma sex hormone binding globulins. It can be converted into estradiol and estrone in peripheral tissue. Testosterone is mostly degraded in the liver, where its A-ring is restored, and it is converted into 17- ketosteroid under the effects of 17β-Hydroxysteroid dehydrogenase. Along with androsterone, epiandrosterone, and etiocholanlone, it is combined with glucuronic acid or sulfate and excreted in urine. Most metabolites in urine that are excreted by binding to glucuronic acid belong to 17-ketosteroids.
Application in Particular Diseases In Osteoporosis:
  • Testosterone replacement is not FDA approved for the prevention or treatment of osteoporosis. It should not be used solely for these indications but might be beneficial to reduce bone loss in patients needing therapy for hypogonadal symptoms. In a few studies, women receiving oral methyltestosterone 1.25 or 2.5 mg daily or testosterone implants 50 mg every 3 months had increased BMD. Various salt forms of testosterone were associated with increased BMD in some studies of hypogonadal men or senior men with normal hormone levels or mild hormonal deficiency. Transdermal gel, oral, intramuscular, and pellet testosterone products are available.
  • Patients using them should be evaluated within 1 to 2 months of initiation and then every 3 to 6 months thereafter.
Chemical Properties white crystalline odourless solid
Uses Secreted by the testis and is converted to dihydrotestosterone in the target tissue where is appears to mediate many of the biological actions of testosterone. CONTROLLED SUBSTANC
Uses Testosterone secreted by the testis is converted to dihydrotestosterone in the target tissues where it appears to mediate many of the biological actions of testosterone. Androgens direct the development of the male phenotype during embryogenesis and at puberty.
Uses androgen, antineoplastic
Uses Testosterone, Principal hormone of the testes, produced by the interstitial cells. Major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone which is required for normal male sexual differentiation. Also converted by aromatization to Estradiol. Testerone is a controlled substance (anabolic steroid). Androgen.
Uses Rivastigmine metabolite
Definition ChEBI: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-41C-5..
Biological Activity Endogenous androgen receptor agonist.

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 

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career henan chemical co

Henan China
  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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