Oxolinic acid
| Price | USD1.00 |
| Packge | 1KG |
- Min. Order:1G
- Supply Ability:100KG
- Time:2019-07-06
Product Details
- Product NameOxolinic acid
- CAS No.14698-29-4
- EINECS No.238-750-8
- MFC13H11NO5
- MW261.23
- InChIKeyKYGZCKSPAKDVKC-UHFFFAOYSA-N
- AppearanceCrystalline PowderWhite
- storage temp. 2-8°C
- Melting point 314-316°C (dec.)
- Boiling point 473℃
- density 1.3038 (rough estimate)
- Water Solubility 3.214mg/L(temperature not stated)
AD68
| Oxolinic acid Basic information |
| Product Name: | Oxolinic acid |
| Synonyms: | 1-ethyl-1,4-dihydro-6,7-methylenedioxy-4-oxo-3-quinolinecarboxylicacid;1-ethyl-6,7-methylenedioxo-4-quinoline-3-carboxlicacid;1-ethyl-6,7-methylenedioxy-4-quinolone-3-carboxylicacid;5-g)quinoline-7-carboxylicacid,5-ethyl-5,8-dihydro-8-oxo-3-dioxolo(4;5-g]quinoline-7-carboxylicacid,5-ethyl-5,8-dihydro-8-oxo-3-dioxolo[4;dioxacin;emyrenil;gramurin |
| CAS: | 14698-29-4 |
| MF: | C13H11NO5 |
| MW: | 261.23 |
| EINECS: | 238-750-8 |
| Product Categories: | Heterocyclic Compounds;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;veterinary medicine,APIs,pharmaceutical raw material;UTIBID;API |
| Mol File: | 14698-29-4.mol |
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| Oxolinic acid Chemical Properties |
| Melting point | 314-316°C (dec.) |
| Boiling point | 473℃ |
| Fp | >110°(230°F) |
| storage temp. | 2-8°C |
| solubility | Soluble in 0.5N NaOH with warming |
| form | Crystalline Powder |
| color | White |
| Sensitive | Light Sensitive |
| Merck | 13,7014 |
| Stability: | Stable. Combustible. |
| CAS DataBase Reference | 14698-29-4(CAS DataBase Reference) |
| EPA Substance Registry System | 1,3-Dioxolo[4,5- g]quinoline-7-carboxylic acid, 5-ethyl-5,8-dihydro-8-oxo- (14698-29-4) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 22-24/25-60-36 |
| WGK Germany | 3 |
| RTECS | JI5075000 |
| F | 10 |
| Hazardous Substances Data | 14698-29-4(Hazardous Substances Data) |
| Toxicity | LD50 in mice, rats (mg/kg): >6000, >2000 orally (Turner) |
| Oxolinic acid Usage And Synthesis |
| Description | Developed in Japan in the 1970s, oxolinic acid belongs to the family of quinolone antibiotic, which is a synthetic antimicrobial agent aiming at gram-negative bacteria, especially those responsible for urinary tract infections. It is also commonly used in clinical for microbiological antimicrobial susceptibility tests against gram negative microbial isolates, providing antibiotic treatment options for infected patients. It can serve as a selective agent in several types of isolation media, for example, to isolate Gardnerella vaginalis. Besides, oxolinic acid can be applied in agriculture, which has proved to be effective against the seed-borne pathogen, such as Burkholderia glumae, a bacteria inducing grain rot, sheath rot, seedling rot, and bacterial panicle blight. Oxolinic acid works by targeting DNA gyrase or topoisomerase II, enzymes vital for DNA synthesis, which ultimately inhibits DNA synthesis and cell division. |
| References | https://en.wikipedia.org/wiki/Oxolinic_acid http://www.toku-e.com/product/oxolinic_acid/ https://www.goldbio.com/product/3027/oxolinic-acid |
| Chemical Properties | Crystalline Solid |
| Uses | Oxolinic acid is a quinolone antibiotic used for studies on DNA winding and coiling and for studies on dopaminergic neurotransmission processes. It is used to study new transmissible resistance mechanisms qnrA, qnrB, qnrS, and aac(6′)Ib-cr, in Escherichia |
| Uses | Quinolone antibacterial. |
| Definition | ChEBI: A quinolinemonocarboxylic acid having the carboxy group at position 7 as well as oxo and ethyl groups at positions 4 and 1 respectively and a dioxolo ring fused at the 5- and 6-positions. A synthetic antibiotic, it is used in veterinary medicine for the tr atment of bacterial infections in cattle, pigs and poultry. |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
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- 2024-01-03
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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