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Lamotrigine
Lamotrigine
Lamotrigine

Lamotrigine

Price USD1.00
Packge 1KG
  • Min. Order:1G
  • Supply Ability:100KG
  • Time:2019-07-06

Product Details

  • Product NameLamotrigine
  • CAS No.84057-84-1
  • EINECS No.281-901-8
  • MFC9H7Cl2N5
  • MW256.09
  • Appearancepowderwhite
  • storage temp. 2-8°C
  • Melting point 177-181°C
  • Boiling point 503.1±60.0 °C(Predicted)
  • density 1.572±0.06 g/cm3(Predicted)

AD68

 
Lamotrigine Basic information
Product Name: Lamotrigine
Synonyms: 4-triazine-3,5-diamine,6-(2,3-dichlorophenyl)-2;3,5-DIAMINO-6-(2,3-DICHLOROPHENYL)-1,2,4-TRIAZINE;6-(2,3-DICHLOROPHENYL)-1,2,4-TRIAZINE-3,5-DIAMINE;LTG;BW-430C;LAMICTAL;LAMOTRIGIN;LAMOTRIGINE
CAS: 84057-84-1
MF: C9H7Cl2N5
MW: 256.09
EINECS: 281-901-8
Product Categories: APIs;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Glutamate receptor;Amines;Heterocycles;Pharmaceutical intermediate;VANTIN;Other APIs
Mol File: 84057-84-1.mol
Lamotrigine Structure
 
Lamotrigine Chemical Properties
Melting point  177-181°C
Fp  9℃
storage temp.  2-8°C
solubility  DMSO: 20 mg/mL at 60 °C, soluble
pka 5.7(at 25℃)
form  powder
color  white
Merck  14,5353
CAS DataBase Reference 84057-84-1(CAS DataBase Reference)
 
Safety Information
Hazard Codes  T,Xi,F
Risk Statements  25-36/37/38-39/23/24/25-23/24/25-11
Safety Statements  45-36-26-36/37-16
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  XY5850700
HazardClass  6.1(b)
PackingGroup  III
Hazardous Substances Data 84057-84-1(Hazardous Substances Data)
Toxicity LD50 in mice, rats (mg/kg): 250, >640 orally (Sawyer)
Lamotrigine Usage And Synthesis
Chemical Properties White to Cream Coloured Powder
Uses An anticonvulsant. Inhibits glutamate release, possible through inhibition of Sodium, Potassium and Calcium currents. Used in treatment of bipolar depression.
Uses antibacterial
Uses For the adjunctive treatment of partial seizures in epilepsy and generalized seizures of Lennox-Gastaut syndrome. Also for the maintenance treatment of bipolar I disorder and depression.
Definition ChEBI: A member of the class of 1,2,4-triazines in which the triazene skeleton is substituted by amino groups at positions 3 and 5, and by a 2,3-dichlorophenyl group at position 6.
Biological Activity Anticonvulsant. Inhibits glutamate release, possibly through inhibition of Na + , K + and Ca 2+ currents.

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 

Recommended supplier

career henan chemical co

Henan China
  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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