morpholin-3-one
| Price | USD1.00 |
| Packge | 1KG |
- Min. Order:1KG
- Supply Ability:Customized
- Time:2019-07-06
Product Details
- Product Namemorpholin-3-one
- CAS No.109-11-5
- EINECS No.203-647-9
- MFC4H7NO2
- MW101.1
- Appearancepowder to crystalWhite to Almost white
- Melting point 103.0 to 107.0 °C
- Boiling point 142°C/7mmHg(lit.)
- density 1.122±0.06 g/cm3(Predicted)
- storage temp. Inert atmosphere,Room Temperature
Product NO: SP906
| morpholin-3-one Basic information |
| Product Name: | morpholin-3-one |
| Synonyms: | Morpholin-3-on;3-Oxomorpholine;MORPHOLIN-3-ONE;3-morpholone;3-MORPHOLINONE;morpholine-3-one;3-Ketomorpholine;Morpholin-3-one ,98% |
| CAS: | 109-11-5 |
| MF: | C4H7NO2 |
| MW: | 101.1 |
| EINECS: | 203-647-9 |
| Product Categories: | Heterocycles;Heterocycles series |
| Mol File: | 109-11-5.mol |
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| morpholin-3-one Chemical Properties |
| Melting point | 103.0 to 107.0 °C |
| Boiling point | 142°C/7mmHg(lit.) |
| CAS DataBase Reference | 109-11-5(CAS DataBase Reference) |
| EPA Substance Registry System | 3-Morpholinone(109-11-5) |
| Safety Information |
| Safety Statements | 24/25 |
| morpholin-3-one Usage And Synthesis |
| Description | 3-ketomorpholine is also known as morpholin-3-one. It is useful pharmacological intermediate. Recent studies have shown that some morpholin-3-one derivatives could effectively cause cell cycle arrest at G1 phase, increase the levels of P53 and Fas, and induce A549 cell apoptosis in lung cancer. This indicates it might be a useful tool for elucidating the molecular mechanism of lung cancer cell apoptosis and might also be potential anti-cancer drugs. Some of its derivatives have been proven to be useful for the prevention and treatment of arteriosclerosis and hypertriglyceridemia. |
| References | He, Q., et al. "Novel morpholin-3-one derivatives induced apoptosis and elevated the level of P53 and Fas in A549 lung cancer cells." Bioorganic & Medicinal Chemistry 15.11(2007): 3889. Murai, Hiromu, et al. "Morpholinone derivatives and method of use." US, US4237132. 1980. Gonzalez-garcia, Maria Rosario, and Fernandez, Maria Carmen. "Morpholinyl derivatives useful as MOGAT-2 inhibitors." (2015). |
| morpholin-3-one Preparation Products And Raw materials |
| Raw materials | Etanol-->Ethyl acetate-->PETROLEUM ETHER-->Toluene-->Sodium hydride -->Ethanolamine-->Methyl bromoacetate |
Company:
Career Henan Chemical Co facing global High-tech pharmaceutical raw materials, high value-added new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade.
Career Henan Chemical Co is adhering to the consistent good commercial reputation, to create a highly efficient, high quality of chemical research, development, production, sales and service of integrated platform, let our customers faster, better get ideal and thoughtful service.
Contacts:
Sophia Han
Tel:86 18623837961
Whatsapp:18623837961
Skype: sophia@coreychem.com
Email:Sophia@coreychem.com
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
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