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Poly(ethylene glycol)
Poly(ethylene glycol)

Poly(ethylene glycol)

Price USD1.00
Packge 1KG
  • Min. Order:1KG
  • Supply Ability:100KG
  • Time:2019-07-06

Product Details

  • Product NamePoly(ethylene glycol)
  • CAS No.25322-68-3
  • EINECS No.203-473-3
  • MF(C2H4O)nH2O
  • MW0
  • InChIKeyVNWKTOKETHGBQD-UHFFFAOYSA-N
  • Appearancewaxy solidWhite to very pale yellow
  • Boiling point >250°C
  • density 1.27 g/mL at 25 °C
  • storage temp. 2-8°C
  • Melting point 64-66 °C
  • Water Solubility Soluble in water.

CR295

 
Poly(ethylene glycol) Chemical Properties
Melting point  64-66 °C
Boiling point  >250°C
density  1.27 g/mL at 25 °C
vapor density  >1 (vs air)
vapor pressure  <0.01 mm Hg ( 20 °C)
refractive index  n20/D 1.469
Fp  270 °C
storage temp.  2-8°C
solubility  H2O: 50 mg/mL, clear, colorless
form  waxy solid
color  White to very pale yellow
PH 5.5-7.0 (25℃, 50mg/mL in H2O)
Water Solubility  Soluble in water.
Sensitive  Hygroscopic
Merck  14,7568
Stability: Stable. Incompatible with strong oxidizing agents.
NIST Chemistry Reference Polyethylene glycol(25322-68-3)
EPA Substance Registry System Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy- (25322-68-3)
 
Safety Information
Hazard Codes  Xi,T
Risk Statements  36/38-52/53-33-23/24/25
Safety Statements  26-36-24/25-61-45-36/37
RIDADR  UN2810 - class 6.1 - PG 3 - EHS - Toxic, liquids, organic, n.o.s., HI: all
WGK Germany  3
RTECS  TQ4110000
F  3-9
Hazard Note  Harmful
TSCA  Yes
HS Code  39072011
Hazardous Substances Data 25322-68-3(Hazardous Substances Data)
MSDS Information
Provider Language
PEG English
SigmaAldrich English
ACROS English
ALFA English
 
Poly(ethylene glycol) Usage And Synthesis
Chemical properties Polyethylene glycol is a polymer which is hydrolyzed by ethylene oxide. It has no toxicity and irritation. It is widely used in various pharmaceutical preparations. The toxicity of low molecular weight polyethylene glycol is relatively large. In general, the toxicity of diols is very low. Topical application of polyethylene glycol, especially mucosal drug, can cause irritant pain. In topical lotion, this product can increase the flexibility of the skin, and has a similar moisturizing effect with glycerin. Diarrhoea can occur in large doses of oral administration. In injection, the maximum polyethylene glycol 300 concentration is about 30% (V/V). Hemolysis could occur when the concentration is more than 40% (V/V).
Application in biomedicine Polyethylene glycol is also known as polyoxirane (PEO). It is a linear polyether obtained by ring opening polymerization of ethylene oxide. The main uses in the field of biomedicine are as follows:
  1. Contact lens liquid. The viscosity of polyethylene glycol solution is sensitive to the shear rate and it is not easy for bacteria to grow on polyethylene glycol.
  2. Synthetic lubricants. The condensation polymer of ethylene oxide and water. It is a cream matrix for preparing water-soluble drugs. It can also be used as a solvent for acetylsalicylic acid and caffeine, which is difficult to dissolve in water.
  3. Drug sustained-release and immobilized enzyme carrier. The polyethylene glycol solution is applied to the outer layer of the pill to control the diffusion of drugs in the pill so as to improve the efficacy.
  4. Surface modification of medical polymer materials. The biocompatibility of medical polymer materials in contact with blood can be improved by adsorption, interception and grafting of two amphiphilic copolymers containing polyethylene glycol on the surface of medical polymers.
  5. It can make the membrane of the alkanol contraceptive pill.
  6. It can make hydrophilic anticoagulant polyurethane.
  7. Polyethylene glycol 4000 is an osmotic laxative. It can increase osmotic pressure and absorb moisture in the intestinal cavity, which makes the stool soften and increase in volume, resulting in bowel movement and defecation.
  8. Denture fixing agent. Peg nontoxic and gelatinous nature can be used as a component of denture fixer.
  9. PEG 4000 and PEG 6000 are commonly used to promote cell fusion or protoplast fusion and help organisms (such as yeasts) to take DNA in transformation. PEG absorbs water from the solution, so it is also used to concentrate the solution.
Chemical Properties White waxy crystalline flakes
Uses Used in conjunction with carbon black to form a conductive composite.1 Polymer nanospheres of poly(ethylene glycol) were used for drug delivery.2
Uses Poly(ethylene Glycol) molecules of approximately 2000 monomers. Poly(ethylene Glycol) is used in various applications from industrial chemistry to biological chemistry. Recent research has shown PEG m aintains the ability to aid the spinal cord injury recovery process, helping the nerve impulse conduction process in animals. In rats, it has been shown to aid in the repair of severed sciatic axons, helping with nerve damage recovery. It is industrially produced as a lubricating substance for various surfaces to reduce friction. PEG is also used in the preparation of vesicle transport systems in with application towards diagnostic procedures or drug delivery methods.
Uses H2 histamine receptor antagonist, anti-ulcer agent
Uses nonionic emulsifier
Uses A polymer used to precipitate proteins, viruses, DNA and RNA
General Description Clear colorless viscous liquid.
Air & Water Reactions Water soluble.
Reactivity Profile Poly(ethylene glycol) is heat-stable and inert to many chemical agents; Poly(ethylene glycol) will not hydrolyze or deteriorate under normal conditions. Poly(ethylene glycol) has a solvent action on some plastics.
Fire Hazard Poly(ethylene glycol) is combustible.
 
Poly(ethylene glycol) Preparation Products And Raw materials
Raw materials Hexane-->ETHYLENE OXIDE-->Poly(ethylene)-->DOYLE DIRHODIUM CATALYST-RH2(4S-MEOX)4-->Aluminium isopropoxide-->Solvent oil No.120
Preparation Products 4-Fluoroaniline-->Polypropylene-->Polyacrylonitrile fiber oil-->2-(5-BROMO-2-PYRIDYLAZO)-5-(DIETHYLAMINO)PHENOL-->Fatty alcohol polyoxyethylene ether N=3-->DIETHOFENCARB-->finishing agent based on water dispersed polysiloxang polyurethane block copolymers-->3-Indolebutyric acid-->softener PEG-->Polyoxyethylene stearate-->Thienamycin-->Water-soluble resin-->antistatic finish agent for synthetic fiber-->Antistatic finishing agent-->polyoxyethylene glycol (600) bislaurate-->rennin B-->softening agent PEN-->efficient defoaming agent JC-5-->C-1 acidic copper plating brightener

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 

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career henan chemical co

Henan China
  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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