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Potassium citrate
Potassium citrate

Potassium citrate

Price USD1455.90USD1426.90
Packge 1000KG1000000KG
  • Min. Order:1000KG
  • Supply Ability:2000T
  • Time:2019-07-06

Product Details

  • Product NamePotassium citrate
  • CAS No.866-84-2
  • EINECS No.212-755-5
  • MFC6H9KO7
  • MW232.23
  • InChIKeyQEEAPRPFLLJWCF-UHFFFAOYSA-K
  • density 1.187
  • Melting point decomposes at 230℃ [KIR78]
  • Water Solubility 60.91 g/100g saturated solution in water (25°C) [MER06]

CR270

Product Name: Potassium citrate
Synonyms: sdTripotassium Citrate;HYDROXY CITRIC ACID SYNTHETIC;2-Hydroxy-1,2,3-propanetricarboxylic acid tripotassium salt;Tripotassium citrate;tripotassium 2-hydroxypropane-1,2,3-tricarboxylate;tripotassiuM citrate anhydrous;potassiuM 2-hydroxypropane-1,2,3-tricarboxylate;Potassium citrate tribasic solution, 1M in water
CAS: 866-84-2
MF: C6H5K3O7
MW: 306.39
EINECS: 212-755-5
Product Categories: Buffer SolutionsBiochemicals and Reagents;ChelatorsProtein Structural Analysis;AlphabeticalBiological Buffers;Biological Buffers;BioUltra Buffers;Optimization Reagents;X-Ray Crystallography;Food additives
Mol File: 866-84-2.mol
Potassium citrate Structure
 
Potassium citrate Chemical Properties
density  1.187
solubility  H2O: 1 M at 20 °C, clear, colorless
PH 8.0-9.5 (25℃, 1M in H2O)
CAS DataBase Reference 866-84-2(CAS DataBase Reference)
EPA Substance Registry System 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, tripotassium salt(866-84-2)
 
Safety Information
WGK Germany  1
Hazardous Substances Data 866-84-2(Hazardous Substances Data)
MSDS Information
 
Potassium citrate Usage And Synthesis
Potassium citrate The applications of potassium citrate (or tripotassium citrate) mainly derive from its alkaline properties. It is used to treat kidney stones composed of uric acid and cysteine, as well as other renal failures caused by excess acidity, including in veterinary applications. As an additive to soft drinks and other edibles, it also functions as an acid buffer, less bitter than other potassium salts, and with less sodium than trisodium citrate.
An additional use of potassium citrate is to supplement potassium in patients with hypokalemia, preventing and treating gout and arrhythmia.
Prevention of urinary calculi drug Potassium citrate is the drug which is most commonly used to prevent calculus. It was found that in the urine pH value and citric acid value and have a very close relationship with the formation urinary tract calculus. In an acidic urine (pH <5.5), the uric acid solubility is very low, so it is likely to cause uric acid calculus; while in alkaline urine (pH> 7), it is easy to form calcium or magnesium phosphate calculus. 63% of urinary calculus patients are below normal urine citrate, and potassium citrate can provide a lot of citric acid to enhance the urine pH value. So for uric acid calculus, It has a very significant therapeutic effect to low calcium citrate calculus disease and tubular poisoning calcium calculus disease. But It will raise the concentration of potassium and lower the concentration of ammonium ion in urinary, which is because not only complements the citric acid, but also supplements of potassium. Since potassium metabolism is very quickly in the body, there is no change in blood potassium concentration. It has little effect on the body. The daily amount of total urine, oxalate, phosphate, sodium, magnesium, sulfate and uric acid and other aspects test from patients with uric acid calculus, it is found that it is not affected by taking potassium citrate.
Chemical properties Colorless crystals or white crystalline powder, odorless, cool and salty, slight deliquescence, soluble in water and glycerin, insoluble in ethanol. Tests show that the product had no significant harm to the human body, ADI doesn’t need special provision (FAO/WHO, 1994).
Uses As a preservative, stabilizing and pH buffering agents and others. China provides for various types of food, according to production needs to use appropriately. 
Used in the food, pharmaceutical and other industries, as buffering agents, chelating agents, flavoring agents, stabilizers, antioxidants, emulsifying salts.
Production methods Citric acid and potassium hydroxide or potassium bicarbonate derived products. 
C6H8O7 + 3KHCO3 → CaH5K3O7 · H2O + 3CO2 ↑ + 2H2O
Reference https://en.wikipedia.org/wiki/Potassium_citrate
https://kidneystones.uchicago.edu/how-citrate-gets-into-the-urine/
https://www.drugbank.ca/drugs/DB09125
http://www.urocit-k.com/
http://www.jungbunzlauer.com/en/products/special-salts/tripotassium-citrate.html
https://www.quora.com/Why-is-potassium-citrate-buffer-is-an-acid-buffer
Uses For use as an electrolyte replenisher and in the treatment of hypokalemia.
Definition ChEBI: The anhydrous form of the tripotassium salt of citric acid.

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 

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  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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