Tetramethylpyrazine
| Price | USD100.00 |
| Packge | 25KG |
- Min. Order:25KG
- Supply Ability:1000KG
- Time:2019-07-06
Product Details
- Product NameTetramethylpyrazine
- CAS No.1124-11-4
- EINECS No.214-391-2
- MFC8H12N2
- MW136.19
- InChIKeyFINHMKGKINIASC-UHFFFAOYSA-N
- AppearanceneatWhite to Off-White
- Melting point 77-80 °C(lit.)
- density 1.08
- Boiling point 190 °C(lit.)
- Water Solubility Soluble in water (4 g/L at 20°C).
- storage temp. Sealed in dry,Room Temperature
CR171
| Product Name: | Tetramethylpyrazine |
| Synonyms: | BS Factor;Ligustrazine;Pyrazine,tetramethyl-;Tetramethylpyrazin;tetramethyl-pyrazin;2,3,5,6-TETRAMETHYLPYRAZINE;2,3,5,6-TETRAMETHYLPYRAZINES;2,3,5,6-TETRAMETHYL-1,4-PYRAZINE |
| CAS: | 1124-11-4 |
| MF: | C8H12N2 |
| MW: | 136.19 |
| EINECS: | 214-391-2 |
| Product Categories: | Pyrazine;Heterocyclic Compounds;Pyrazines;Mono- & Polyalkylpyrazines;pyrazine Flavor;Alphabetical Listings;Flavors and Fragrances;Q-Z;Certified Natural ProductsFlavors and Fragrances;Building Blocks;Heterocyclic Building Blocks;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors |
| Mol File: | 1124-11-4.mol |
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| Tetramethylpyrazine Chemical Properties |
| Melting point | 77-80 °C(lit.) |
| Boiling point | 190 °C(lit.) |
| density | 1.08 |
| FEMA | 3237 |
| Fp | 128-130°C/200mm |
| storage temp. | Store below +30°C. |
| solubility | 4g/l |
| Water Solubility | Soluble in water (4 g/L at 20°C). |
| BRN | 113100 |
| Stability: | Stable. Incompatible with strong acids, strong oxidizing agents. |
| CAS DataBase Reference | 1124-11-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Pyrazine, tetramethyl-(1124-11-4) |
| EPA Substance Registry System | Pyrazine, tetramethyl-(1124-11-4) |
| Safety Information |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-37/38-41-36/37/38 |
| Safety Statements | 26-39-24/25-37/39-36 |
| WGK Germany | 3 |
| RTECS | UQ3905000 |
| TSCA | Yes |
| HS Code | 29339990 |
| MSDS Information |
| Provider | Language |
|---|---|
| Tetramethylpyrazine | English |
| ACROS | English |
| SigmaAldrich | English |
| ALFA | English |
| Tetramethylpyrazine Usage And Synthesis |
| Description | Tetramethylpyrazine (TMP) is a kind of alkaloids identified in Ligusticum wallichii FRANCH. It has various kinds of medical applications. It has long been used in China for the treatment of cardiovascular problems. It also has antiinflammatory and analgesic effect. It can be used for the treatment of diabetic peripheral neuropathy. Through effectively penetrating across the blood-brain barrier, it can exert its neuroprotection function which is useful for the treatment of ischemic brain injury. Moreover, it can eliminate superoxide anion and decreases nitric oxide production in human polymorphonuclear leukocytes. |
| Chemical Characteristic | White crystal or powder. With aroma of beef and heated lard and fermented soybean flavor. It smells chocolate flavor when diluted to 20mg/kg. Boiling point is 190℃. Melting point is between 84 and 86℃. Soluble in ethanol, most non-volatile oils and propylene glycol, slightly soluble in water. Natural products exist in guava, roast beef, cocoa, coffee, shrimp and so on. |
| Uses |
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| Preparation |
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| References | TH Tsai, CC Liang. International Journal of Pharmaceutics, 216. 1-2 (2001) WU, Zhi-youg, et al. Chinese Journal of Experimental Traditional Medical Formulae 14 (2012): 085. Ozaki, Yukihiro. Chemical and pharmaceutical bulletin 40.4 (1992): 954-956. Kao, Tsung-Kuei, et al. Neurochemistry international 48.3 (2006): 166-176. Zhang, Zhaohui, et al. Life sciences 72.22 (2003): 2465-2472. |
| Chemical Properties | white crystals or powder |
| Uses | Usually used in research and treatment of multiple disorders. |
| Definition | ChEBI: A member of the class of pyrazines that is pyrazine in which all four hydrogens have been replaced by methyl groups. An alkaloid extracted from Chuanxiong (Ligusticum wallichii). |
| Tetramethylpyrazine Preparation Products And Raw materials |
| Raw materials | Sodium nitrite-->2,3-Butanedione-->Acetylacetone-->1,4-DIAMINOBUTANE-->Ethyl nitrite-->2-Methylpyrazine |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
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- 2024-02-24
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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