Nonivamide
| Price | USD300.00 |
| Packge | 1KG |
- Min. Order:10G
- Supply Ability:customise
- Time:2019-07-06
Product Details
- Product NameNonivamide
- CAS No.2444-46-4
- EINECS No.219-484-1
- MFC17H27NO3
- MW293.4
- Appearancepowderwhite to off-white
- storage temp. Sealed in dry,2-8°C
- Melting point 54°C
- density 1,1 g/cm3
- Boiling point 200-210 °C(Press: 0.05 Torr)
Product Number：WM0172
| Product Name: | Nonivamide |
| Synonyms: | Nonivamide(Synthetic Capsaicin);N-((Hydroxy-3-methoxyphenyl)methyl)4-nonanamide;N-Nonanoyl vanillylamide;Nonanamide, N-((4-hydroxy-3-methoxyphenyl)meth;n-((4-hydroxy-3-methoxyphenyl)methyl)-nonanamid;n-[(4-hydroxy-3-methoxyphenyl)methyl]-nonanamid;Nonanoylvanilylamide;nonylicacidvanillylamide(nonivamide) |
| CAS: | 2444-46-4 |
| MF: | C17H27NO3 |
| MW: | 293.4 |
| EINECS: | 219-484-1 |
| Product Categories: | Inhibitors;API;INORGANIC & ORGANIC CHEMICALS;Anilines, Aromatic Amines and Nitro Compounds;Plant extract;Herb extract |
| Mol File: | 2444-46-4.mol |
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| Nonivamide Chemical Properties |
| Melting point | 54°C |
| density | 1,1 g/cm3 |
| FEMA | 2787 | NONANOYL 4-HYDROXY-3-METHOXYBENZYLAMIDE |
| Fp | 190°C |
| storage temp. | 2-8°C |
| solubility | methanol: 100 mg/mL, clear to slightly hazy |
| form | powder |
| color | white to off-white |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 2444-46-4(CAS DataBase Reference) |
| EPA Substance Registry System | Nonanamide, N-[(4-hydroxy-3-methoxyphenyl) methyl]-(2444-46-4) |
| Safety Information |
| Hazard Codes | T,Xi |
| Risk Statements | 25-36/37/38-43 |
| Safety Statements | 26-45-37/39-36/37 |
| RIDADR | UN 3462 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | RA5998000 |
| F | 19 |
| HazardClass | 6.1 |
| PackingGroup | II |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| Nonivamide Usage And Synthesis |
| Description | Nonivamide is also called pelargonic acid vanillylamide or PAVA. It is a capsaicinoid. Nonivamide, isolated from peppers, is a naturally occurring analog of capsaicin (sc-3577). Similar to capsaicin, nonivamide can activate the TRPV1 receptor, thus, stimulate the firing rate of dopaminergic neurons in the ventral tegmental area of the brain and to increase the expression of the serotonin receptor gene HTR2A. Nonivamide is with lower TRPV1 binding affinity, thus, a reduced pungency (9 200 000 scoville heat units) compared to capsaicin (16 000 000 scoville heat units). Nonivamide is used in the food production to add a hot sensation to flavoring agents and spice mixtures. It is also used in the sweets and confectionary industries to add hot sensation into products. In pharmaceutical industries, nonivamide is used as a cheaper alternative for capsaicin. Warming or heating ointment of nonivamide is used for temporary relief of pain from conditions such as rheumatism, arthritis, lumbao, muscular aches, sprains and strains, sporting injuries and other conditions where local warmth is beneficial. Finalgon is one of the common product utilizing nonivamide for this purpose. Nonivamide is also used as an incapacitant spray, affecting the assailed person’s eyes, causing intense pain and swelling. |
| References | [1] https://www.scbt.com/scbt/product/nonivamide-2444-46-4 [2] https://pubchem.ncbi.nlm.nih.gov/compound/N-Vanillylnonanamide#section=Clinical-Trials [3] https://cot.food.gov.uk/sites/default/files/cot/cotsection.pdf |
| Chemical Properties | solid |
| Uses | analgesic (topical), depletes Substance P |
| Uses | N-Vanillylnonanamide is a synthetic analogue of Capsaicin (175680) with similar bioactivity. |
| Definition | ChEBI: A capsaicinoid that is the carboxamide resulting from the formal condensation of the amino group of 4-hydroxy-3-methoxybenzylamine with the carboxy group of nonanoic acid. It is the active ingredient in many pepper sprays. |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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