298-46-4
| Price | USD1000.00 |
| Packge | 1KG |
- Min. Order:1KG
- Supply Ability:2000kg
- Time:2019-07-06
Product Details
- Product Name298-46-4
- CAS No.Carbamazepine
- EINECS No.206-062-7
- MFC15H12N2O
- MW236.27
- InChIKeyFFGPTBGBLSHEPO-UHFFFAOYSA-N
- AppearanceCrystalsAlmost white
- Water Solubility pract. insoluble
- storage temp. 2-8°C
- Melting point 191-192 °C (lit.)
- Boiling point 378.73°C (rough estimate)
- density 1.1099 (rough estimate)
CR65
| Carbamazepine Basic information |
| Product Name: | Carbamazepine |
| Synonyms: | Oxcarbazepine IMpurity A;CarbaMazepine (D10, 98%);CarbaMazepine (D10, 98%) 100 ug/Ml In CH3CN-D3;CarbaMazepine (D10, 98%) 100 ug/Ml In MeOH;CarbaMazepine-13C6;Carbamazepine solution ;CARBAMAZEPIN;CARBAMAZEPINE |
| CAS: | 298-46-4 |
| MF: | C15H12N2O |
| MW: | 236.27 |
| EINECS: | 206-062-7 |
| Product Categories: | Pharmaceutical raw material;TEGRETOL;Pharmaceutical;Acids and Derivatives;Heterocycles;Active Pharmaceutical Ingredients;APIs;Pharmaceutical Chemicals;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics;Isotope Labelled Compounds |
| Mol File: | 298-46-4.mol |
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| Carbamazepine Chemical Properties |
| Melting point | 189-192 °C |
| Fp | 9℃ |
| storage temp. | 2-8°C |
| solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble29mg/mL |
| form | Crystals |
| color | Almost white |
| Water Solubility | pract. insoluble |
| Merck | 14,1781 |
| CAS DataBase Reference | 298-46-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Carbamazepine(298-46-4) |
| Safety Information |
| Hazard Codes | Xn,T,F |
| Risk Statements | 42/43-22-20/21/22-39/23/24/25-23/24/25-11 |
| Safety Statements | 37-24-22-36/37/39-36-45-36/37-16 |
| RTECS | HN8225000 |
| HS Code | 29339900 |
| Hazardous Substances Data | 298-46-4(Hazardous Substances Data) |
| MSDS Information |
| Provider | Language |
|---|---|
| Carbamazepine | English |
| ACROS | English |
| Carbamazepine Usage And Synthesis |
| Chemical Properties | White Solid |
| Uses | analgesic, anticonvulsant |
| Uses | Used in treatment of pain associated with trigeminal neuralgia. Anticonvulsant |
| Definition | ChEBI: A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant. |
| Uses | Carbamazepine (CBZ) is a first generation anticonvulsant and mood stabilizing compound that has been used as a therapeutic in the context of neuropathic pain, epilepsy, and affective disorders. It exerts its effects by blocking voltage-gated sodium channels (IC50 = 640 μM), making fewer of these channels available to subsequently open, which leads to decreased high-frequency repetitive firing of action potentials. The estimated IC50 values for inhibition of Nav1.7-, Nav1.3-, and Nav1.8-type channels by CBZ following prolonged inactivation have been reported as 406, 900, and 138 μM, respectively. CBZ can also inhibit L-type Ca2+ channels (IC50 = 974 μM) and has been shown to potentiate GABAA receptors (IC50 >3 mM). |
| Carbamazepine Preparation Products And Raw materials |
| Raw materials | 2-Nitrotoluene-->Iminostilbene-->2,2'-ETHYLENEDIANILINE |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
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- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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