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Afatinib
Afatinib

Afatinib

Price USD100.00
Packge 1KG
  • Min. Order:1KG
  • Supply Ability:500KG
  • Time:2019-07-06

Product Details

  • Product NameAfatinib
  • CAS No.850140-72-6
  • MFC24H25ClFN5O3
  • MW485.94
  • AppearanceYellow powder.Pale yellow
  • density 1.380
  • Boiling point 676.9±55.0 °C(Predicted)
  • Melting point 102 °C
  • storage temp. -20°C

1.Product No.: GC090

2.Basical information:

Afatinib Basic information
Product Name: Afatinib
Synonyms: Afatinib;(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide;4-[(3-chloro-4-fluorophenyl)aMino]-6-{[4-(N,N-diMethylaMino)-1-oxo-2-buten-1-yl]aMino}-7-((S)-tetrahydrofuran-3-yloxy)-quinazoline;2-ButenaMide, N-[4-[(3-chloro-4-fluorophenyl)aMino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(diMethylaMino)-, (2E)-;(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dime;Afatinib API;Afatinib(BIBW2992MA2);Afatinib (with 1 int.)
CAS: 850140-72-6
MF: C24H25ClFN5O3
MW: 485.9384032
EINECS:  
Product Categories: Amines;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;tyrosine kinase receptor inhibitor;Antineoplastic;Afatinib
Mol File: 850140-72-6.mol
Afatinib Structure
 
Afatinib Chemical Properties
density  1.380
Afatinib Usage And Synthesis
Uses An aminocrotonylamino-substituted quinazoline derivative
Definition ChEBI: A quinazoline compound having a 3-chloro-4-fluoroanilino group at the 4-position, a 4-dimethylamino-trans-but-2-enamido group at the 6-position, and an (S)-tetrahydrofuran-3-yloxy group at the 7-position. Used (as its di aleate salt) for the first-line treatment of patients with metastatic non-small cell lung cancer.

Any interests of this material, pls kindly send us inquiry: grace@coreychem.com or call me at +86-17093661273 directly.

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 

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career henan chemical co

Henan China
  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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